Trial reportJournal of clinical monitoring and computing2025
A novel wearable bioimpedance sensor for continuous monitoring of fluid balance: a study on isotonic hypovolemia in healthy adults.
Trial report in Journal of clinical monitoring and computing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05129358 (Testing of an Electronic Patch During Dehydration in Healthy Volunteers), which is not on this map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Testing of an Electronic Patch During Dehydration in Healthy Volunteers
Who cites it
4 citing papers in PubMed.
- Analysis of biological systems using bioimpedance spectroscopy: a critical review of technological convergence and translational challenges.Frontiers in bioengineering and biotechnology · 2026Review
- Hemodynamic Monitoring During Hemodialysis Using Bioimpedance: A Comparison of Changes in Resistance Between Different Body Segments.Hemodialysis international. International Symposium on Home Hemodialysis · 2025Observational
- Wearable and noninvasive monitoring of fluid shifts: A pilot study assessing a novel bioimpedance sensor during lower body negative pressure.Physiological reports · 2025Article
- Wireless arm-worn bioimpedance sensor for continuous assessment of whole-body hydration.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
purposeThis study aimed to investigate the ability of a novel wearable bioimpedance sensor to monitor changes in fluid balance induced by furosemide. Because iso-osmotic fluid loss is expected to primarily comprise fluid from the extracellular compartment it was hypothesized that isotonic hypovolemia would increase the extracellular resistance (R
methods27 healthy adults (20 women, 7 men; 35 ± 10 year.) were continuously monitored by the bioimpedance sensor following administration of furosemide. Body weight, blood pressure, heart rate, sensation of thirst and selected blood parameters were tested before furosemide administration (t0), one hour (t1) and two hours (t2) after furosemide administration, and one hour after intake of a sports drink containing carbohydrate and electrolytes (t3). Urine elimination was measured throughout the intervention, and the change in extracellular fluid volume was estimated using urine elimination and established equations.
resultsDuring hypovolemia body weight was reduced by 1.4 ± 0.2 kg (1.7 ± 0.4%). Total urine elimination during fluid loss was 1277 ± 190 mL. R
conclusionThis study demonstrates that the wearable bioimpedance device tested is very sensitive to furosemide-induced changes in fluid volume in healthy volunteers in a controlled environment. Additional research is needed to evaluate the ability of the device to track fluid status in a clinical setting.
trial registrationThe study was registered at clinicaltrials.gov 29th of October 2021 (NCT05129358).
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