Evidence map›Paper›PMID 39630284›Full record

ArticleSurgery today2025

Status of perioperative venous thromboembolism (VTE) prophylaxis in gastrointestinal surgery based on national clinical database (NCD) data in Japan.

Taishi Hata, Hiroyuki Yamamoto, Masataka Ikeda, Hiroaki Nagano, Ichiro Takemasa, Takeshi Naitoh, Norikazu Yamada, Mamoru Uemura, Hidetoshi Eguchi, Yoshihiro Kakeji and 2 more

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Article in Surgery today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Taishi HataDepartment of Surgery, Kansai Rosai Hospital, Inabaso, Amagasaki, Hyogo, Japan. hata-taishi@kansaih.johas.go.jp.ORCID http://orcid.org/0000-0003-1680-724X
Hiroyuki YamamotoDepartment of Healthcare Quality Assessment, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Masataka IkedaDivision of Lower GI, Department of Gastroenterological Surgery, Hyogo Medical University, Hyogo, Japan.
Hiroaki NaganoDepartment of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan.
Ichiro TakemasaDepartment of Surgery, Surgical Oncology and Science, Sapporo Medical University, Hokkaido, Japan.
Takeshi NaitohDepartment of Lower Gastrointestinal Surgery, Kitasato University School of Medicine, Kanagawa, Japan.
Norikazu YamadaDepartment of Cardiology, Kuwana City Medical Center, Mie, Japan.
Mamoru UemuraDepartment of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Hidetoshi EguchiDepartment of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Yoshihiro KakejiDatabase Committee, The Japanese Society of Gastroenterological Surgery, Tokyo, Japan.
Ken ShirabeThe Japanese Society of Gastroenterological Surgery, Tokyo, Japan.
Yuichiro DokiDepartment of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the current status of perioperative venous thromboembolism (VTE) prophylaxis in gastrointestinal surgery in Japan.

methodsWe reviewed data on eight gastroenterological procedures from the Japanese National Clinical Database (NCD), accrued between 2018 and 2020. Patient characteristics, prophylactic methods, postoperative bleeding, cardiac arrest, and postoperative mortality rate within 30 days were retrieved.

resultsDespite recommendations, approximately 30% of patients did not receive VTE prophylaxis, suggesting a lack of awareness. Pharmacological prophylaxis was associated with a higher incidence of VTE than mechanical or no prophylaxis for all procedures. Combined prophylaxis resulted in a lower incidence of VTE than pharmacological prophylaxis alone. Pharmacological prophylaxis was also associated with an increased incidence of bleeding events. The risk of cardiac arrest and death was higher in patients with pulmonary embolism (PE), but there was a trend toward lower mortality in the group that received pharmacological prophylaxis.

conclusionPharmacological prophylaxis for VTE was limited in reducing the incidence of VTE, but it may reduce the risk of death. Combining pharmacological and mechanical prophylaxis tended to be more effective for preventing VTE than either method alone. Conversely, pharmacological prophylaxis may increase the risk of bleeding.

Indexed as

AnticoagulantsDatabases, FactualDigestive System Surgical ProceduresPerioperative CarePostoperative ComplicationsVenous ThromboembolismAgedAged, 80 and overFemaleHeart ArrestHumansIncidenceJapanMaleMiddle AgedPerioperative PeriodAnticoagulantsGastrointestinal surgeryNational clinical databasePostoperative outcomesProphylaxisVenous thromboembolism

Identifiers

PMID39630284

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.