Evidence map›Paper›PMID 39630241›Full record

ArticlePediatric radiology2025

Real-world impact of high-pitch helical CT on radiation exposure and image quality in infants being evaluated for cardiothoracic pathologies.

Joshua G Hunter, Kaustav Bera, Leslie Ciancibello, Syed Muhammad Awais Bukhari, Jennifer Sposato, Kianoush Ansari Gilani, Robert Gilkeson, Amit Gupta

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Article in Pediatric radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joshua G HunterCase Western Reserve University School of Medicine, 9501 Euclid Ave, Cleveland, OH, USA. jgh82@case.edu.
Kaustav BeraDepartment of Radiology, University Hospitals Cleveland Medical Center, Cleveland, USA.
Leslie CiancibelloDepartment of Radiology, University Hospitals Cleveland Medical Center, Cleveland, USA.
Syed Muhammad Awais BukhariDepartment of Radiology, University Hospitals Cleveland Medical Center, Cleveland, USA.
Jennifer SposatoDepartment of Radiology, University Hospitals Cleveland Medical Center, Cleveland, USA.
Kianoush Ansari GilaniDepartment of Radiology, University Hospitals Cleveland Medical Center, Cleveland, USA.
Robert GilkesonDepartment of Radiology, University Hospitals Cleveland Medical Center, Cleveland, USA.
Amit GuptaDepartment of Radiology, University Hospitals Cleveland Medical Center, Cleveland, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvaluation of cardiothoracic pathologies is a common indication for computed tomography (CT) in infants. However, CT is fraught with challenges specific to the patient population, such as increased sensitivity to radiation and inability to remain stationary during imaging.

objectiveThis study investigates potential advantages of a high-pitch helical CT protocol for infants with cardiothoracic pathologies. Namely, we evaluate whether a high-pitch helical CT protocol can minimize radiation exposure without compromising image quality. MATERIALS AND

methodsThis retrospective study included 98 consecutive cardiac protocol CT examinations of infants (56 males, 42 females; mean age 3.3 ± 2.8 months) performed at a tube voltage of 80 kV between 2016 and 2022. Forty-seven examinations were acquired with a non-gated conventional helical protocol on a multi-detector CT scanner (control group) and 51 were acquired with a non-gated high-pitch helical protocol on a dual-source CT scanner (high-pitch (HP) group). Patient characteristics, radiation exposure parameters, and imaging datasets were extracted from the picture archiving and communication system (PACS). Image quality was assessed subjectively by two radiologists who independently assigned ratings, and objectively through attenuation measurements.

resultsRadiation exposure was approximately 75% lower in the HP group (0.54 mSv vs. 2.46 mSv, P < .001). HP examinations demonstrated comparable, or better, image quality across all metrics in both subjective and objective analyses. In the subjective analysis, the HP group achieved superior ratings for visualization of the aorta (P = .04). In the objective analysis, the HP group achieved superior signal-to-noise ratio (SNR) in the left atrium (P < .001), left ventricle (P = .04), and aorta (P = .003), and superior contrast-to-noise ratio (CNR) in the left atrium (P = .003) and aorta (P = .009).

conclusionOur findings suggest that employing high-pitch helical CT protocols for evaluation of cardiothoracic pathologies in infants decreases radiation exposure while achieving similar to slightly better image quality compared to conventional helical CT protocols.

Indexed as

Heart Defects, CongenitalRadiation DosageRadiation ExposureTomography, Spiral ComputedFemaleHumansInfantInfant, NewbornMaleRadiographic Image Interpretation, Computer-AssistedRetrospective StudiesCardiothoracicHigh-pitch CTImage qualityInfantPatient throughput

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.