Evidence map›Paper›PMID 39629752›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2025

Clinical Outcome Assessments for Spasticity: Review, Critique, and Recommendations.

Ota Gal, Marjolaine Baude, Thierry Deltombe, Alberto Esquenazi, Jean-Michel Gracies, Martina Hoskovcova, Carmen Rodriguez-Blazquez, Raymond Rosales, Lalith Satkunam, Jörg Wissel and 6 more

Abstract readScoping Review
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  7. Review
  8. Review
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  10. Ultrasound-Derived Stretch Reflex Threshold Estimation Using Tendon-to-Bone Distance During Tendon Tapping in Post-Stroke Spasticity.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026
    Article
  11. Article
  12. Spastic Ataxia Composite (SPAXCOM): A Scale to Evaluate the Progression of Subjects with Spasticity and Ataxia.Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
  13. Article
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  15. Reliability of the Five Step Assessment and Its Coefficients of Impairment in Spastic Paresis.Archives of rehabilitation research and clinical translation · 2025
    Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ota GalDepartment of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine, Charles University, Prague, Czech Republic.ORCID https://orcid.org/0000-0002-8614-2776
Marjolaine BaudeService de Rééducation Neurolocomotrice, Hôpitaux Universitaires Henri-Mondor, Assistance publique-Hôpitaux de Paris, Créteil, France.
Thierry DeltombeDepartment of Physical Medicine & Rehabilitation, CHU UCL Namur Site Godinne, Yvoir, Belgium.
Alberto EsquenaziJefferson Moss-Magee Rehabilitation, Philadelphia, Pennsylvania, USA.
Jean-Michel GraciesBIOTN Laboratory, EA 7377 BIOTN, Université Paris-Est Créteil, Créteil, France.
Martina HoskovcovaDepartment of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Carmen Rodriguez-BlazquezNational Centre of Epidemiology, Institute of Health Carlos III, Madrid, Spain.
Raymond RosalesFaculty of Medicine and Surgery-Research Center for Health Sciences and Dept. Of Neuroscience, University of Santo Tomas (and Hospital), Manila, Philippines.
Lalith SatkunamDivision of Physical Medicine & Rehabilitation, Glenrose Rehabilitation Hospital, Edmonton, Alberta, Canada.
Jörg WisselNeurology and Psychosomatic at Wittenbergplatz, Berlin, Germany.ORCID https://orcid.org/0000-0001-6238-3578
Tiago MestreParkinson's Disease and Movement Disorders Clinic, Division of Neurology, Department of Medicine, The Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Álvaro Sánchez-FerroCIBERNED, Institute of Health Carlos III, Madrid, Spain.
Matej SkorvanekDepartment of Neurology, P. J. Šafárik University, Košice, Slovakia.ORCID https://orcid.org/0000-0001-5497-8715
Michelle Hyczy de Siqueira TosinDepartment of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0001-7309-1407
Robert JechDepartment of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine, Charles University, Prague, Czech Republic.ORCID https://orcid.org/0000-0002-9732-8947
members of the MDS Clinical Outcome Assessments Scientific Evaluation Committee and MDS Spasticity Study group

Funding

National Institute for Neurological Research Progamme EXCELES LX22NPO5107
6 · The paper itself

Abstract

backgroundSpasticity is a common feature in patients with disruptions in corticospinal pathways. However, the term is used ambiguously. Here, spasticity is defined as enhanced velocity-dependent stretch reflexes and placed within the context of deforming spastic paresis encompassing other forms of muscle overactivity.

objectiveThis scoping review aims at evaluating the clinimetric quality of clinical outcome assessments (COAs) for spasticity across different pathologies and to make recommendations for their use.

methodsA literature search was conducted to identify COAs used to assess spasticity. An international expert panel evaluated the measurement properties in the included COAs. Recommendations were based on the MDS-COA program methodology based on three criteria: if the COA was (1) applied to patients with spastic paresis, (2) used by others beyond the developers, and (3) determined to be reliable, valid, and sensitive to change in patients with spasticity.

resultsWe identified 72 COAs of which 17 clinician-reported outcomes (ClinROs) and 6 patient-reported outcomes (PROs) were reviewed. The Tardieu Scale was the only ClinRO recommended for assessing spasticity. One ClinRO-Composite Spasticity Index-and two PROs-Spasticity 0-10 Numeric Rating Scale and 88-Item Multiple Sclerosis Spasticity Scale-were recommended with caveats. The Ashworth-derived COAs were excluded after evaluation due to their focus on muscle tone rather than spasticity, as defined in this review.

conclusionsThe Tardieu Scale is recommended for assessing spasticity, and two PROs are recommended with caveats. Consistent terminology about the various types of muscle overactivity is necessary to facilitate their assessment and treatment. © 2024 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Indexed as

Muscle SpasticityOutcome Assessment, Health CareHumansmuscle hypertoniamuscle overactivitymuscle spasticitypsychometricsrating scalesreviewspastic paresis

Identifiers

PMID39629752
PMCPMC11752990

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.