ArticleJournal of family medicine and primary care2024
"Is it time to initiate scrub typhus surveillance in Karnataka?"-Lessons from a seroprevalence survey in a rural district.
Article in Journal of family medicine and primary care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Scrub typhus, caused by Methods: A pilot cross-sectional survey was conducted between October and December 2022 among eligible asymptomatic adults from five randomly selected villages of the Bangalore Rural District after obtaining written informed consent. Serum immunoglobin M (IgM) and immunoglobin G (IgG) antibodies were tested using the respective enzyme-linked immunosorbent assay (ELISA) kits from InBios International Inc, Seattle, USA. Seroprevalence was defined as positivity to either IgG or IgM antibodies or both. Results: The study reported a seroprevalence of 8.9% (95% CI 4.8%-14.7%) among 146 asymptomatic adults. The IgG and IgM antibodies were positive in 7.5% and 2.1% of participants, respectively. Conclusions: A community seroprevalence of 8.9% warrants further epidemiological surveys and surveillance in the context of climate change, variable clinical presentations of scrub typhus, and the possible need to include this disease in the clinical practice algorithm in the primary care setting. We recommend study designs with "One Health" lens to monitor the trend of this re-emerging public health problem.
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