Evidence map›Paper›PMID 39629386›Full record

ArticleJournal of family medicine and primary care2024

Correlation between CRP and ferritin in dengue patients: A hospital-based prospective observational study.

Sailendra Nayak, Rabinarayan Rout, Bandita Panda, Mourya Machipeddy, Vibha Sharma, Shubhransu Patro

Abstract read
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Article in Journal of family medicine and primary care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Sailendra NayakDepartment of General Medicine, Kalinga Institute of Medical Sciences, KIIT DU, Bhubaneswar, Odisha, India.
Rabinarayan RoutDepartment of General Medicine, Kalinga Institute of Medical Sciences, KIIT DU, Bhubaneswar, Odisha, India.
Bandita PandaDepartment of Research and Development, Kalinga Institute of Medical Sciences, KIIT DU, Bhubaneswar, Odisha, India.
Mourya MachipeddyDepartment of General Medicine, Kalinga Institute of Medical Sciences, KIIT DU, Bhubaneswar, Odisha, India.
Vibha SharmaDepartment of General Medicine, Kalinga Institute of Medical Sciences, KIIT DU, Bhubaneswar, Odisha, India.
Shubhransu PatroDepartment of General Medicine, Kalinga Institute of Medical Sciences, KIIT DU, Bhubaneswar, Odisha, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In India, dengue is one of the health challenges and a leading cause of hospitalization, especially during the monsoon. C-reactive protein (CRP) is an independent marker for dengue severity. The present study aimed to analyze the correlation between CRP and ferritin and with other hematological markers in dengue fever (DF). Methods: A hospital-based prospective study was conducted over one year. With the patient's consent, A total of 189 dengue-diagnosed hospitalized patients aged more than 18 years were included in the study group. Demographic features, total leukocytes, total platelet counts, packed cell volume, CRP, and ferritin were monitored in both severe and non-severe cases. Significant univariate parameters were correlated and significant associations were analyzed from the correlation coefficient and Result: A total of 189 dengue-diagnosed, hospitalized patients were recruited, among them 30 patients were diagnosed as severe and 159 patients were diagnosed as non-severe. The mean age ranged between 41 ± 16.7 and 42 ± 15.9 years. In univariate analysis, total leucocytes, CRP, and ferritin were significantly higher in dengue severe cases in comparison to non-severe dengue cases. The association between CRP and ferritin revealed a positive correlation whereas, the association between ferritin and total platelet count showed a negative correlation. Conclusion: A significant positive correlation between CRP and ferritin indicates that ferritin can be an additional biomarker along with CRP for the hospitalization of dengue patients and may be useful for severity prediction at an early stage of infection.

Indexed as

C-reactive protein (CRP)dengue feverferritintotal leucocytetotal platelet count

Identifiers

PMID39629386
PMCPMC11610826

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