ReviewEngineering microbiology2021
Integrated engineering of enzymes and microorganisms for improving the efficiency of industrial lignocellulose deconstruction.
Review in Engineering microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Deciphering How Clustered O‑Glycosylation Shapes Substrate-Binding Preferences in an Intrinsically Disordered Protein Region.JACS Au · 2026Article
- Improvement of the capacity to hydrolyze corncob residues through deciphering the lignocellulolytic enzyme system of a hyper-cellulolytic mutant strain Trichoderma reesei CU7-4.Biotechnology for biofuels and bioproducts · 2025Article
- SGBP-B-like bimodular cellulose-binding protein CHU_1279 is essential for cellulose utilization byApplied and environmental microbiology · 2025Article
- Structural changes and cellulose ultrastructure mapped with electron microscopy and SAXS after enzymatic hydrolysis of mildly steam pretreated Norway spruce.Biotechnology for biofuels and bioproducts · 2025Article
- Acetate production from corn stover hydrolysate using recombinant Escherichia coli BL21 (DE3) with an EP-bifido pathway.Microbial cell factories · 2024Article
- Construction of an alternative NADPH regeneration pathway improves ethanol production inSynthetic and systems biotechnology · 2024Article
- An efficient CRISPR/Cas9 genome editing system based on a multiple sgRNA processing platform in Trichoderma reesei for strain improvement and enzyme production.Biotechnology for biofuels and bioproducts · 2024Article
- Structure-guided engineering of transcriptional activator XYR1 for inducer-free production of lignocellulolytic enzymes inSynthetic and systems biotechnology · 2023Article
- Engineered yeasts and lignocellulosic biomaterials: shaping a new dimension for biorefinery and global bioeconomy.Bioengineered · 2023Review
- A novel transcriptional repressor specifically regulates xylanase gene 1 in Trichoderma reesei.Biotechnology for biofuels and bioproducts · 2023Article
- Dynamics of loops surrounding the active site architecture in GH5_2 subfamily TfCel5A for cellulose degradation.Biotechnology for biofuels and bioproducts · 2023Article
- Cost-effective production of alginate oligosaccharides from Laminaria japonica roots by Pseudoalteromonas agarivorans A3.Microbial cell factories · 2023Article
- Profiling proteomic responses to hexokinase-II depletion in terpene-producingEngineering microbiology · 2023Article
- Engineering ofEngineering microbiology · 2023Review
- Characterization of a New Glucose-Tolerant GH1 β-Glycosidase fromInternational journal of molecular sciences · 2023Article
- The ERAD Pathway Participates in Fungal Growth and Cellulase Secretion inJournal of fungi (Basel, Switzerland) · 2023Article
- Strain improvement ofFrontiers in microbiology · 2023Review
- Plastid Transformation: New Challenges in the Circular Economy Era.International journal of molecular sciences · 2022Review
- Elimination of the Sugar Transporter GAT1 Increased Xylanase I Production inFrontiers in microbiology · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bioconversion of lignocellulosic biomass to fuels and chemicals represents a new manufacturing paradigm that can help address society's energy, resource, and environmental problems. However, the low efficiency and high cost of lignocellulolytic enzymes currently used hinder their use in the industrial deconstruction of lignocellulose. To overcome these challenges, research efforts have focused on engineering the properties, synergy, and production of lignocellulolytic enzymes. First, lignocellulolytic enzymes' catalytic efficiency, stability, and tolerance to inhibitory compounds have been improved through enzyme mining and engineering. Second, synergistic actions between different enzyme components have been strengthened to construct customized enzyme cocktails for the degradation of specific lignocellulosic substrates. Third, biological processes for protein synthesis and cell morphogenesis in microorganisms have been engineered to achieve a high level and low-cost production of lignocellulolytic enzymes. In this review, the relevant progresses and challenges in these fields are summarized. Integrated engineering is proposed to be essential to achieve cost-effective enzymatic deconstruction of lignocellulose in the future.
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Registered trials
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