Evidence map›Paper›PMID 39628790›Full record

ArticleEngineering microbiology2024

Identification and application of a strong bidirectional

Sainan Li, Danfeng Tang, Xu Zhao, Manxiang Zhu, Xiangcheng Zhu, Yanwen Duan, Yong Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Engineering microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sainan LiXiangya International Academy of Translational Medicine, Central South University, Changsha 410013, China.
Danfeng TangXiangya International Academy of Translational Medicine, Central South University, Changsha 410013, China.
Xu ZhaoInstitute of Health and Medicine, Hefei Comprehensive National Science Center, Hefei 230093, China.
Manxiang ZhuInstitute of Health and Medicine, Hefei Comprehensive National Science Center, Hefei 230093, China.
Xiangcheng ZhuXiangya International Academy of Translational Medicine, Central South University, Changsha 410013, China.
Yanwen DuanXiangya International Academy of Translational Medicine, Central South University, Changsha 410013, China.
Yong HuangXiangya International Academy of Translational Medicine, Central South University, Changsha 410013, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural product biosynthesis is controlled at multiple levels. Characterization of naturally occurring promoters has facilitated the study of the synthetic biology of natural products. Herein, we report the discovery of two high-yield actinomycin D (ActD)-producing streptomycetes and the identification of a strong bidirectional acmN2p promoter from the ActD gene clusters and its application in heterologous expression of three core genes involved in the bacterial alkaloid bohemamine biosynthesis, providing a good example for identification of new promoters for synthetic biological applications.

Indexed as

Actinomycin DBidirectional promoterBohemamineStreptomyces

Identifiers

PMID39628790
PMCPMC11610978

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.