Evidence map›Paper›PMID 39628751›Full record

ArticleCureus2024

Cholestatic Hepatitis: A Rare Manifestation of Infectious Mononucleosis.

Francisco Barreto, Sofia Nóbrega, Carolina Carvalhinha, Carolina Henriques, Teresa Faria

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francisco BarretoInternal Medicine, Hospital Central do Funchal, Funchal, PRT.
Sofia NóbregaInternal Medicine, Hospital Central do Funchal, Funchal, PRT.
Carolina CarvalhinhaInternal Medicine, Hospital Central do Funchal, Funchal, PRT.
Carolina HenriquesInternal Medicine, Hospital Central do Funchal, Funchal, PRT.
Teresa FariaInternal Medicine, Hospital Central do Funchal, Funchal, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the main clinical manifestations of infection by the Epstein-Barr virus (EBV) is infectious mononucleosis. In this clinical syndrome, mild hepatitis with a slight elevation of aminotransferases is common. However, cholestasis is rare and usually occurs alongside a more severe, cytolytic hepatitis. This case report describes a 26-year-old male admitted to the emergency service with recurrent fever, odynophagia, and painful cervical lymphadenopathy, along with a skin rash after starting treatment with amoxicillin/clavulanate, and jaundice. The analytical assessment was consistent with cholestatic hepatitis, and the abdominal CT scan revealed hepatosplenomegaly. The diagnosis of EBV infection was confirmed by the presence of serological markers. This case aims to raise awareness of a rare manifestation of a common infectious agent in order to consider acute EBV infection in the differential diagnosis of cholestatic hepatitis in adult patients.

Indexed as

cholestasischolestatic hepatitisepstein-barr virushepatitisjaundice

Identifiers

PMID39628751
PMCPMC11614552

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.