Evidence map›Paper›PMID 39628747›Full record

ArticleCureus2024

Transient Regression of Breast Carcinoma After Diagnostic Biopsy and Tumor Heterogeneity: A Case Report.

Eduardo De Faria Castro Fleury, Jose Augusto de Sousa Neto, Sheila Cristina L Wludarski, Edson M Barbosa

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Spontaneous Regression in Pancreatic Neuroendocrine Tumor.Internal medicine (Tokyo, Japan) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eduardo De Faria Castro FleuryRadiology, MD duFLE Diagnósticos, São Paulo, BRA.
Jose Augusto de Sousa NetoMastology, Instituto Brasileiro de Controle do Câncer, São Paulo, BRA.
Sheila Cristina L WludarskiPathology, Instituto Hermes Pardini, Grupo Fleury, Sao Paulo, BRA.
Edson M BarbosaMastology, Instituto Brasileiro de Controle do Câncer, São Paulo, BRA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous cancer regression is a rare biological phenomenon; however, the mechanisms involved in this process are still poorly understood. We report the case of a 92-year-old woman with a histological diagnosis of breast carcinoma. On the date of the scheduled surgical resection of her tumor, she did not present the initial lesion diagnosed by biopsy, on clinical examination. The patient underwent mammography and breast magnetic resonance imaging, which confirmed the absence of the initial tumor. Due to religious beliefs, the patient refused additional specific treatment with her family's approval. In consensus with her family, we proposed imaging follow-up to assess tumor recurrence, which lasted for 18 months. In this article, we discuss the theory that the local trauma generated by the diagnostic percutaneous biopsy triggered an immune response responsible for the phenomenon of tumor regression. The secondary objective is to discuss the transformation in the histological type of tumor cell.

Indexed as

histologic remissionimmunogenic cell death (icd)primary breast malignancyspontaneous regression of cancertumor heterogeneity

Identifiers

PMID39628747
PMCPMC11614558

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.