ReviewCureus2024
Cystoid Macular Edema Related to Uncomplicated Cataract Surgery and Topical Prostaglandin Analogs: A Systematic Review of Randomized Controlled Trials.
Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Cystoid macular edema following travoprost intracameral implant.American journal of ophthalmology case reports · 2026Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCystoid macular edema (CME) presents with thickening of the macula with an accumulation of fluid due to breakage of the inner and outer blood-retinal barriers. It is referred to as pseudophakic CME (PCME) if it occurs after cataract surgery. PGF2a is a prostaglandin analog (PGA) used to lower intraocular pressure (IOP). In uncomplicated cataract surgery, the cumulative effect of topical PGA can make clinically significant PCME more prevalent. There are conflicting data regarding the association of PCME and the use of PGA in the perioperative period of uncomplicated cataract surgery, and its use remains controversial. We aim to determine the effect of PGA usage in the perioperative period in cases of uncomplicated cataract surgery on the development of PCME. METHODOLOGY: A systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) in seven electronic databases was performed. The main outcome measure included the development of PCME diagnosed by clinical examination, OCT, or FA of adult patients (age > 16 years) undergoing routine cataract surgery using PGA in the perioperative period reported in randomized controlled trials.
resultsThe search returned 196 articles, and 155 unique citations were identified after removing duplicates. According to the inclusion and exclusion criteria, four studies were selected for our review. They did not find a measurable effect on PCME incidence by PGA in the perioperative period in patients undergoing cataract surgery.
conclusionThe results show no causal relationship between PCME in patients using PGA undergoing uneventful cataract surgery, suggesting they do not have to be suspended in patients without known risk factors of PCME.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.