Evidence map›Paper›PMID 39628697›Full record

ArticleInternational journal of medical sciences2024

Zuojin Pill enhances gastrointestinal motility by modulating the pacemaker potentials in interstitial cells of Cajal through multiple signaling pathways.

Jueun Lee, Seok Jae Ko, Na Ri Choi, Woo-Gyun Choi, Mujin Seo, Seung Hyeon Koo, Daehwa Jung, Min Jae Lee, Jong Hwan Lee, Jae-Woo Park and 1 more

Abstract read
In one paragraph

Article in International journal of medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jueun LeeDepartment of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University, Yangsan 50612, Republic of Korea.
Seok Jae KoDepartment of Clinical Korean Medicine, Graduate School of Kyung Hee University, Seoul 02447, Republic of Korea.
Na Ri ChoiDepartment of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University, Yangsan 50612, Republic of Korea.
Woo-Gyun ChoiDepartment of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University, Yangsan 50612, Republic of Korea.
Mujin SeoDepartment of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University, Yangsan 50612, Republic of Korea.
Seung Hyeon KooDepartment of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University, Yangsan 50612, Republic of Korea.
Daehwa JungDepartment of Pharmaceutical Engineering, Daegu Hanny University, Gyeongsan 38610, Republic of Korea.
Min Jae LeeCollege of Veterinary Medicine, Kangwon National University, Chuncheon 24341, Republic of Korea.
Jong Hwan LeeDepartment of Biomedical Engineering, Dong-Eui University College of Engineering, Busan 47340, Republic of Korea.
Jae-Woo ParkDepartment of Clinical Korean Medicine, Graduate School of Kyung Hee University, Seoul 02447, Republic of Korea.
Byung Joo KimDepartment of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University, Yangsan 50612, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zuojin Pill (ZJP) is a traditional herbal preparation used to treat various gastrointestinal (GI) disorders. The purpose of this study was to elucidate the underlying cellular and molecular mechanisms by evaluating the effects of ZJP on the pacemaker activity of isolated interstitial cells of Cajal (ICCs) and on

Indexed as

Drugs, Chinese HerbalGastrointestinal MotilityInterstitial Cells of CajalAnimalsCalcium SignalingHumansIntestine, SmallMaleMicePatch-Clamp TechniquesPiperidinesReceptor, Muscarinic M3Signal Transduction4-diphenylacetoxy-1,1-dimethylpiperidiniumDrugs, Chinese HerbalPiperidinesReceptor, Muscarinic M3Gastrointestinal DisordersInterstitial Cells of CajalIntestinal Transit RatePacemaker PotentialZuojin Pill

Identifiers

PMID39628697
PMCPMC11610331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.