Evidence map›Paper›PMID 39628487›Full record

ReviewFrontiers in immunology2024

Scientific issues with rodent models of neuromyelitis optic spectrum disorders.

Yusen Huang, Tianwei Wang, Fangruyue Wang, Yujing Wu, Jia Ai, Ying Zhang, Meiyan Shao, Le Fang

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yusen Huang *Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, China.
Tianwei Wang *Department of Radiology, China-Japan Union Hospital of Jilin University, Changchun, China.
Fangruyue WangThe Third Bethune Hospital of Jilin University, Changchun, China.
Yujing WuThe Third Bethune Hospital of Jilin University, Changchun, China.
Jia AiThe Third Bethune Hospital of Jilin University, Changchun, China.
Ying ZhangThe Third Bethune Hospital of Jilin University, Changchun, China.
Meiyan ShaoDepartment of Neurology, China-Japan Union Hospital of Jilin University, Changchun, China.
Le FangDepartment of Neurology, China-Japan Union Hospital of Jilin University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuromyelitis optica spectrum disorders (NMOSD) is a rare autoimmune disorder that causes severe inflammation in the central nervous system (CNS), primarily affecting the optic nerves, spinal cord, and brainstem. Aquaporin-4 immunoglobulin G antibodies (AQP4-IgG) are a diagnostic marker of the disease and play a significant role in its pathogenesis, though the exact mechanism is not yet fully understood. To develop rodent models that best simulate the

Indexed as

Aquaporin 4AutoantibodiesBlood-Brain BarrierDisease Models, AnimalNeuromyelitis OpticaAnimalsHumansImmunoglobulin GMiceRatsRodentiaAquaporin 4AutoantibodiesImmunoglobulin Ganimal modelAQP4-IgGautoantibodiesautoimmune disordersneuromyelitis optica spectrum disorders

Identifiers

PMID39628487
PMCPMC11611858

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.