ArticleClinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery2025
Quality of Information Provided by Artificial Intelligence Chatbots Surrounding the Reconstructive Surgery for Head and Neck Cancer: A Comparative Analysis Between ChatGPT4 and Claude2.
Article in Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Commercial large language models for oral cavity cancer staging using descriptive pre-treatment MRI reports: ready for standalone use in clinical practice?Insights into imaging · 2026Article
- Survey on Chinese users' acceptance of AI assistants: expanding technology acceptance model.Scientific reports · 2025Article
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19 authors.
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Abstract
introductionArtificial Intelligences (AIs) are changing the way information is accessed and consumed globally. This study aims to evaluate the information quality provided by AIs ChatGPT4 and Claude2 concerning reconstructive surgery for head and neck cancer.
methodsThirty questions on reconstructive surgery for head and neck cancer were directed to both AIs and 16 head and neck surgeons assessed the responses using the QAMAI questionnaire. A 5-point Likert scale was used to assess accuracy, clarity, relevance, completeness, sources, and usefulness. Questions were categorised into those suitable for patients (group 1) and those for surgeons (group 2). AI responses were compared using t-Student and McNemar tests. Surgeon score agreement was measured with intraclass correlation coefficient, and readability was assessed with Flesch-Kincaid Grade Level (FKGL).
resultsChatGPT4 and Claude2 had similar overall mean scores of accuracy, clarity, relevance, completeness and usefulness, while Claude2 outperformed ChatGPT4 in sources (110.0 vs. 92.1, p < 0.001). Considering the group 2, Claude2 showed significantly lower accuracy and completeness scores compared to ChatGPT4 (p = 0.003 and p = 0.002, respectively). Regarding readability, ChatGPT4 presented lower complexity than Claude2 (FKGL mean score 4.57 vs. 6.05, p < 0.001) requiring an easy-fairly easy English in 93% of cases.
conclusionOur findings indicate that neither chatbot exhibits a decisive superiority in all aspects. Nonetheless, ChatGPT4 demonstrates greater accuracy and comprehensiveness for specific types of questions and the simpler language used may aid patient inquiries. However, many evaluators disagree with chatbot information, highlighting that AI systems cannot serve as a substitute for advice from medical professionals.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.