Evidence map›Paper›PMID 39628384›Full record

ArticleEmerging microbes & infections2025

Predictive metabolite signatures for risk of progression to active TB from QuantiFERON supernatants of household contacts of TB patients.

Evangeline Ann Daniel, Shubham Upadhyay, Murugesan Selvachithiram, Sathyamurthi Pattabiraman, Brindha Bhanu, Amsaveni Sivaprakasam, Vandana Kulkarni, Rajesh Karyakarte, Sanjay Gaikwad, Mandar Paradkar and 5 more

Abstract read
In one paragraph

Article in Emerging microbes & infections, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Evangeline Ann DanielDepartment of Virology and Biotechnology, National Institute for Research in Tuberculosis, Indian Council of Medical Research (ICMR), Chennai, India.ORCID 0000-0002-7378-717X
Shubham UpadhyayCenter for Systems Biology and Molecular Medicine, Yenepoya University, Mangalore, India.ORCID 0000-0002-2237-4420
Murugesan SelvachithiramDepartment of Virology and Biotechnology, National Institute for Research in Tuberculosis, Indian Council of Medical Research (ICMR), Chennai, India.
Sathyamurthi PattabiramanDepartment of Virology and Biotechnology, National Institute for Research in Tuberculosis, Indian Council of Medical Research (ICMR), Chennai, India.ORCID 0000-0002-6530-3518
Brindha BhanuDepartment of Virology and Biotechnology, National Institute for Research in Tuberculosis, Indian Council of Medical Research (ICMR), Chennai, India.
Amsaveni SivaprakasamDepartment of Virology and Biotechnology, National Institute for Research in Tuberculosis, Indian Council of Medical Research (ICMR), Chennai, India.
Vandana KulkarniBJ Government Medical College-Johns Hopkins Clinical Research Site, Pune, India.ORCID 0000-0002-3488-2692
Rajesh KaryakarteByramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India.ORCID 0000-0002-2005-9283
Sanjay GaikwadByramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India.ORCID 0000-0002-2411-0373
Mandar ParadkarJohns Hopkins Center for Infectious Diseases in India, Pune, India.ORCID 0000-0001-9843-4656
Shri Vijay Bala Yogendra ShivakumarJohns Hopkins Center for Infectious Diseases in India, Pune, India.ORCID 0000-0003-0935-8423
Vidya MaveJohns Hopkins Center for Infectious Diseases in India, Pune, India.ORCID 0000-0001-8509-4517
Amita GuptaJohns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-7036-2718
Keshava PrasadCenter for Systems Biology and Molecular Medicine, Yenepoya University, Mangalore, India.ORCID 0000-0002-6206-2384
Luke Elizabeth HannaDepartment of Virology and Biotechnology, National Institute for Research in Tuberculosis, Indian Council of Medical Research (ICMR), Chennai, India.ORCID 0000-0001-7338-1631

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The identification of individuals with the greatest risk of progression to active tuberculosis (TB) disease from the huge reservoir of

Indexed as

Mycobacterium tuberculosisTuberculosisAdultDisease ProgressionFamily CharacteristicsFemaleHumansInterferon-gamma Release TestsMaleMetabolomeMiddle AgedProspective StudiesYoung AdultbiomarkersdiagnosisMetabolitesmetabolite signaturesprogressionQuantiFERON supernatanttuberculosis

Identifiers

PMID39628384
PMCPMC11703509

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.