Evidence map›Paper›PMID 39628297›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2025

Bilateral waveform analysis of gait biomechanics presurgery to 12 months following ACL reconstruction compared to controls.

Christin Büttner, Caroline Lisee, Elizabeth Bjornsen, Ashley Buck, Natália Favoreto, Alexander Creighton, Ganesh Kamath, Jeffrey Spang, Jason R Franz, Troy Blackburn and 1 more

Abstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Step-by-step insight into gait analysis: A narrative review unlocking knee biomechanics.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Gait Biomechanical Profiles Following Anterior Cruciate Ligament Reconstruction in Sexually-Immature Pediatrics.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Bilateral waveform analysis of gait biomechanics presurgery to 12 months following ACL reconstruction compared to controls.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Christin BüttnerDepartment of Exercise and Sport Science, University of North Carolina, Chapel Hill, North Carolina, USA.ORCID 0000-0002-6864-6890
Caroline LiseeDepartment of Kinesiology, University of Georgia, Athens, Georgia, USA.
Elizabeth BjornsenJoint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, North Carolina, USA.
Ashley BuckDepartment of Exercise and Sport Science, University of North Carolina, Chapel Hill, North Carolina, USA.ORCID 0000-0002-1811-612X
Natália FavoretoDepartment of Exercise and Sport Science, University of North Carolina, Chapel Hill, North Carolina, USA.
Alexander CreightonDeparment of Orthopaedics, University of North Carolina, Chapel Hill, North Carolina, USA.
Ganesh KamathDeparment of Orthopaedics, University of North Carolina, Chapel Hill, North Carolina, USA.
Jeffrey SpangDeparment of Orthopaedics, University of North Carolina, Chapel Hill, North Carolina, USA.
Jason R FranzJoint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, North Carolina, USA.
Troy BlackburnDepartment of Exercise and Sport Science, University of North Carolina, Chapel Hill, North Carolina, USA.ORCID 0000-0003-0878-9432
Brian PietrosimoneDepartment of Exercise and Sport Science, University of North Carolina, Chapel Hill, North Carolina, USA.

Funding

UNC Core Center for Clinical ResearchP30AR072580 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LEIGH Fleming CALLAHAN, Amanda E Nelson · 2019 to 2026
$6.1M
The Rheumatic and Musculoskeletal Disease Epidemiology and Outcomes Training Program at the University of North CarolinaT32AR082310 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LEIGH Fleming CALLAHAN, Amanda E Nelson · 2024 to 2026
$616k
ARTHFNNIAMS NIH HHS P30 AR072580NIAMS NIH HHS P30AR072580NIAMS NIH HHS T32 AR082310NIAMS NIH HHS T32AR082310
6 · The paper itself

Abstract

The purpose of this study was to compare gait biomechanics between limbs and to matched uninjured controls (i.e., sex, age, and body mass index) preoperatively and at 2, 4, 6, and 12 months following primary unilateral anterior cruciate ligament reconstruction (ACLR). Functional mixed effects models were used to identify differences in gait biomechanics throughout the stance phase between the a) ACLR limb and uninvolved limb, b) ACLR limb and controls, and c) uninvolved limb and controls. Compared with the uninvolved limb, the ACLR limb demonstrated lesser knee extension moment (KEM; within 8-37% range of stance) during early stance as well as lesser knee flexion moment (KFM; 45-84%) and greater knee flexion angle (KFA; 43-90%) during mid- to late stance at all timepoints. Compared with controls, the ACLR limb demonstrated lesser vertical ground reaction force (vGRF; 5-26%), lesser KEM (7-47%), and lesser knee adduction moment (KAM; 12-35%) during early stance as well as greater vGRF (39-63%) and greater KFA (34-95%) during mid- to late stance at all timepoints. Compared with controls, the uninvolved limb demonstrated lesser KFA (1-56%) and lesser KEM (12-54%) during early to mid-stance at all timepoints. While gait becomes more symmetrical over the first 12 months post-ACLR, the ACLR and uninvolved limbs both demonstrate persistent aberrant gait biomechanics compared to controls. Biomechanical waveforms throughout stance can be generally described as less dynamic following ACL injury and ACLR compared with uninjured controls.

Indexed as

Anterior Cruciate Ligament ReconstructionGaitAdolescentAdultAnterior Cruciate Ligament InjuriesBiomechanical PhenomenaCase-Control StudiesFemaleHumansMaleYoung Adultfunctional mixed effects modeljoint loadingknee osteoarthritis

Identifiers

PMID39628297
PMCPMC11701409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.