Evidence map›Paper›PMID 39627889›Full record

ReviewAnimal models and experimental medicine2025

Rat models of frozen shoulder: Classification and evaluation.

Hezirui Gu, Wenqing Xie, Hengzhen Li, Shuguang Liu, Yusheng Li

Abstract readReview
In one paragraph

Review in Animal models and experimental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Evaluation of the Antifibrotic and Functional Effects of Pirfenidone in an Experimental Frozen Shoulder Model.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Article
  3. Article
  4. Article
  5. Rat models of frozen shoulder: Classification and evaluation.Animal models and experimental medicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hezirui GuDepartment of Orthopedics, Xiangya Hospital, Central South University, Changsha, China.
Wenqing XieDepartment of Orthopedics, Xiangya Hospital, Central South University, Changsha, China.
Hengzhen LiDepartment of Orthopedics, Xiangya Hospital, Central South University, Changsha, China.
Shuguang LiuDepartment of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, China.
Yusheng LiDepartment of Orthopedics, Xiangya Hospital, Central South University, Changsha, China.ORCID 0000-0002-3404-0807

Funding

National Key R&D Program of China 2019YFA0111900National Key R&D Program of China 2021YFC2502100National Key R&D Program of China 2023YFC3603404The Hunan Provincial Innovation Foundation for Postgraduate CX20230308The Hunan Provincial Innovation Foundation for Postgraduate CX20230312The Hunan Provincial Science Fund for Distinguished Young Scholars 2024JJ2089The Hunan Young Talents of Science and Technology 2021RC3025The Independent Exploration and Innovation Project for Postgraduate Students of Central South University 2024ZZTS0163The National Clinical Research Center for Geriatric Disorders, Xiangya Hospital 2021KFJJ02The National Clinical Research Center for Geriatric Disorders, Xiangya Hospital 2021LNJJ05The National Natural Science Foundation of China 82072506The National Natural Science Foundation of China 82272611The National Natural Science Foundation of China 92268115The National Natural Science Foundation of Hunan Province 2023JJ30949The Provincial Clinical Medical Technology Innovation Project of Hunan 2020SK53709The Provincial Clinical Medical Technology Innovation Project of Hunan 2023SK2024The Provincial Natural Science Foundation of Hunan 2020JJ3060
6 · The paper itself

Abstract

Frozen shoulder (FS), also known as adhesive capsulitis, is a condition that causes contraction and stiffness of the shoulder joint capsule. The main symptoms are persistent shoulder pain and a limited range of motion in all directions. These symptoms and poor prognosis affect people's physical health and quality of life. Currently, the specific mechanisms of FS remain unclear, and there is variability in treatment methods and their efficacy. Additionally, the early symptoms of FS are difficult to distinguish from those of other shoulder diseases, complicating early diagnosis and treatment. Therefore, it is necessary to develop and utilize animal models to understand the pathogenesis of FS and to explore treatment strategies, providing insights into the prevention and treatment of human FS. This paper reviews the rat models available for FS research, including external immobilization models, surgical internal immobilization models, injection modeling models, and endocrine modeling models. It introduces the basic procedures for these models and compares and analyzes the advantages, disadvantages, and applicability of each modeling method. Finally, our paper summarizes the common methods for evaluating FS rat models.

Indexed as

BursitisDisease Models, AnimalAnimalsHumansRatsShoulder Jointendocrine modelinginjectionrat modelsurgical internal immobilization

Identifiers

PMID39627889
PMCPMC11798749

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.