ArticleBreast cancer research : BCR2024
Social vulnerability is associated with advanced breast cancer presentation and all-cause mortality: a retrospective cohort study.
Article in Breast cancer research : BCR, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Utility of the Social Vulnerability Index in Addressing Breast Cancer Disparities: A Meta-Analysis.Journal of surgical oncology · 2025Pooled it
- Examining the Role of the Social Vulnerability Index in the Association between Race/Ethnicity and Breast Cancer Outcomes.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026Article
- Association of hospital quality and social determinants of health with short-term surgical outcomes among medicare beneficiary patients undergoing elective cancer surgery.American journal of surgery · 2026Article
- Immigration and Social Factors, Tumor Stage, and Risk of Contralateral Breast Cancer in Asian American and Hispanic Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026Article
- Differential effects of neighborhood ambient PMInternational journal of health geographics · 2026Article
- Census tract-level socioeconomic variables and breast cancer characteristics and outcomes in California and New York State.Cancer causes & control : CCC · 2026Article
- Characterizing Treatment Delays in Patients With HPV-Negative Oropharyngeal Cancer.Cancer medicine · 2026Article
- Association of Neighborhood Social Vulnerability With Metastatic Cancer at Diagnosis.Cancer medicine · 2026Article
- Overall survival, poverty differentials, and mediating pathways among women with breast cancer: South African Breast Cancer and HIV Outcomes cohort.The oncologist · 2025Article
- Effect of race and ethnicity on advanced breast cancer risk prediction model performance.NPJ digital medicine · 2025Article
- Association of social vulnerability with access to treatment in ovarian cancer patients.Gynecologic oncology reports · 2025Article
- All-cause mortality and neighborhood social vulnerability among women with ovarian cancer.Gynecologic oncology · 2025Article
- Effect of Social Determinants of Health and Geography on Uveal Melanoma.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundDisparities in breast cancer mortality persist despite improvements in screening and therapeutic options. Understanding the impact of social determinants of health on disparate breast cancer outcomes is challenging due to heterogeneity of prior assessments. We examined the association between social vulnerability and breast cancer stage at diagnosis and mortality using a standardized measure of population risk for external stressors on health.
methodsUsing institutional cancer registry data, female patients aged 18 or older diagnosed with breast cancer between 2012 and 2019 were assigned a 2018 Social Vulnerability Index (SVI) rank based upon home address census tract. We used multinomial logistic regression and Cox proportional hazards model to examine the relationships between SVI and breast cancer stage at diagnosis and all-cause mortality. Covariates included age and, when assessing mortality, cancer stage, comorbidities, body mass index, insurance type, and treatment regimen.
resultsA total of 3,499 women with a median age of 59 (IQR 48-69) were included. 60% were White and 31% were Black. Median SVI was 0.36 (IQR 0.14-0.68) and median follow-up was 58 months (IQR 37.3-83.9). On adjusted analyses, each decile increase in SVI resulted in an 11% (OR 1.11, 95% CI 1.06-1.16, p < .001) and 15% (OR 1.15, 95% CI 1.09-1.21, p < .001) greater odds of presenting with Stage III or IV breast cancer, respectively, compared to DCIS. For patients who underwent surgery (N = 2916), each decile increase in SVI was associated with a 6% increase in all-cause mortality risk (HR 1.06, 95% CI 1.01-1.12, p = .01). Mortality risk was 1.5 times (HR 1.52, 95% CI 1.02-2.26, p = .04) greater for those in the most vulnerable quartile compared to the least vulnerable quartile.
conclusionsWomen living in socially vulnerable communities presented with more advanced breast cancers and suffered worse survival. The SVI can be used to identify patients at risk for delayed cancer presentation and increased mortality. This tool can inform geographically targeted resource allocation and interventions aimed at reducing breast cancer care disparities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.