Evidence map›Paper›PMID 39627831›Full record

ArticleTrials2024

The clinical effects of pulsed electromagnetic field therapy for the management of chronic ankle instability: a study protocol for a double-blind randomized controlled trial.

Cheryl Shu Ming Chia, Sai-Chuen Fu, Xin He, Yang Yang Cheng, Alfredo Franco-Obregón, Yinghui Hua, Patrick Shu-Hang Yung, Samuel Ka-Kin Ling

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05500885 (The Clinical Effectiveness of Pulsed Electromagnetic Field Therapy on the Management of Chronic Ankle Instability), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05500885 nacompletednot on this map

The Clinical Effectiveness of Pulsed Electromagnetic Field Therapy on the Management of Chronic Ankle Instability: A Double-Blinded Randomized Controlled Trial

TypeinterventionalSponsorChinese University of Hong KongRan2023 to 2025Enrolled62ConditionsChronic Ankle InstabilityArmsPEMF device, Quantum Tx, Singapore, Standard rehabilitation and sham PEMF therapy for CAI
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cheryl Shu Ming ChiaDepartment of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong (CUHK), Sha Tin, Hong Kong, China.
Sai-Chuen FuDepartment of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong (CUHK), Sha Tin, Hong Kong, China.
Xin HeDepartment of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong (CUHK), Sha Tin, Hong Kong, China.
Yang Yang ChengDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Alfredo Franco-ObregónDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore.
Yinghui HuaDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Patrick Shu-Hang YungDepartment of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong (CUHK), Sha Tin, Hong Kong, China.
Samuel Ka-Kin LingDepartment of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong (CUHK), Sha Tin, Hong Kong, China. samuel.ling@link.cuhk.edu.hk.ORCID http://orcid.org/0000-0003-4528-9074

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic ankle instability is associated with long-term neuromuscular deficits involving poor postural control and peroneal muscular impairment. Symptoms of chronic ankle instability hinder engagement in physical activity and undermine the patient's quality of life. Despite the existence of various treatment modalities, none has conclusively provided evidence of clinical effectiveness in counteracting neuromuscular deficits, such as arthrogenic muscle inhibition of the peroneal longus (PL). Pulse electromagnetic field therapy employed as an adjunct biophysical therapy can potentially improve stability by mitigating peroneal muscle weakness and by activating the peroneal muscle. We postulate that by combining standard care (muscle strengthening, balance training, and range of motion exercise) with pulse electromagnetic field therapy, postural control stability and peroneal muscle weakness will significantly improve.

methodsThis is a prospective, randomized, double-blind, placebo-controlled trial. A total of 48 adults with chronic ankle instability will be recruited and randomly allocated into either the intervention or control groups. The intervention group (n = 24) will receive active pulse electromagnetic field therapy and standard exercise training, while the control group (n = 24) will receive sham pulse electromagnetic field therapy and standard exercise training for 8 weeks. Primary and secondary outcomes will be evaluated at baseline, week 4, 8 as well as at 3-, 6-, and 12-month follow-up visits. DISCUSSION: Chronic ankle instability is a common debilitating condition without a curative conservative treatment. Investigating different treatment modalities will be essential for improving rehabilitation outcomes in this clinical population. This study will investigate the effectiveness of pulsed electromagnetic field therapy on the functional and clinical outcomes in the chronic ankle instability population. This trial may demonstrate this non-invasive biophysical therapy to be an effective measure to help patients with CAI.

trial registrationClinicalTrials.gov NCT05500885. Registered on August 13, 2022.

Indexed as

Ankle JointJoint InstabilityMagnetic Field TherapyRandomized Controlled Trials as TopicAdultChronic DiseaseDouble-Blind MethodExercise TherapyFemaleHumansMaleMiddle AgedPostural BalanceProspective StudiesRange of Motion, ArticularRecovery of FunctionAnkle sprainAnterior talofibular ligamentChronic ankle instabilityPulse electromagnetic fieldRandomized controlled trial

Identifiers

PMID39627831
PMCPMC11613907

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.