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ArticleRadiological physics and technology2025

Can bile excretion on Gd-EOB-MRI be used as a visual criterion for the hepatobiliary phase?

Masafumi Nakamura, Yasuo Takatsu, Mutsumi Yoshizawa, Satoshi Kobayashi, Tosiaki Miyati

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Article in Radiological physics and technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Masafumi NakamuraDepartment of Radiological Technology, Faculty of Health and Welfare, Tokushima Bunri University, 1314-1, Shido, Sanuki, Kagawa, 769-2193, Japan. nakamuraxx2@gmail.com.ORCID http://orcid.org/0000-0003-2520-8628
Yasuo TakatsuDivision of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, Ishikawa, 920-0942, Japan.ORCID http://orcid.org/0000-0002-4384-089X
Mutsumi YoshizawaDepartment of Radiology, Otsu City Hospital, 2-9-9, Motomiya, Otsu, Shiga, 520-0804, Japan.
Satoshi KobayashiDivision of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, Ishikawa, 920-0942, Japan.ORCID http://orcid.org/0000-0001-7759-399X
Tosiaki MiyatiDivision of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, Ishikawa, 920-0942, Japan.ORCID http://orcid.org/0000-0001-6120-2990

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To determine whether visually observed biliary excretion of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) can be used to assess contrast adequacy of hepatobiliary phase (HBP) images. Images of 121 patients undergoing Gd-EOB-DTPA-enhanced magnetic resonance imaging were used. Adequate HBP images were defined as a quantitative liver-spleen contrast ratio (Q-LSC) ≥ 1.5. Visual evaluation was performed to determine if an adequate HBP image could be obtained based on the presence or absence of bile excretion. Common bile duct-paravertebral contrast (CPC) was used to assess the degree of bile excretion, the albumin-bilirubin (ALBI) grade was used to assess liver reserve, and the Q-LSC was used to assess HBP image contrast. The results were used to quantitatively evaluate the relationships of the degree of bile excretion with HBP image contrast and liver reserve. The cases correctly determined by visual evaluation via bile excretion were 80 (66.1%) at HBP 10 min after injection and 89 (73.6%) at HBP 20 min after injection. Among cases with Q-LSC ≥ 1.5 indicating bile excretion, there were 33 cases at HBP 10 min after injection and 86 cases at HBP 20 min after injection. Furthermore, among cases with Q-LSC < 1.5, indicating no bile excretion, there were 47 cases at HBP 10 min after injection and 3 cases at HBP 20 min after injection. Visually observed biliary excretion of Gd-EOB-DTPA is not a criterion for adequate HBP image contrast.

Indexed as

BileBiliary TractGadolinium DTPALiverMagnetic Resonance ImagingAdultAgedAged, 80 and overContrast MediaFemaleHumansMaleMiddle AgedYoung AdultContrast MediaGadolinium DTPAgadolinium ethoxybenzyl DTPABile excretionGadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acidHepatobiliary phaseMagnetic resonance imaging

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.