Evidence map›Paper›PMID 39627646›Full record

SynthesisWorld journal of pediatrics : WJP2024

Epidemic risks of measles and rubella in China: a systematic review and meta-analysis.

Yi-Tong Lin, Yi-Xuan Gao, Yan Zhang, Ai-Li Cui, Hui-Ling Wang, Zhen Zhu, Nai-Ying Mao

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in World journal of pediatrics : WJP, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yi-Tong LinNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, WHO WPRO Regional Reference Measles/Rubella Laboratory, Chinese Centre for Disease Control and Prevention, No.155 Changbai Road, Changping District, Beijing, China.
Yi-Xuan GaoNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, WHO WPRO Regional Reference Measles/Rubella Laboratory, Chinese Centre for Disease Control and Prevention, No.155 Changbai Road, Changping District, Beijing, China.
Yan ZhangNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, WHO WPRO Regional Reference Measles/Rubella Laboratory, Chinese Centre for Disease Control and Prevention, No.155 Changbai Road, Changping District, Beijing, China.
Ai-Li CuiNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, WHO WPRO Regional Reference Measles/Rubella Laboratory, Chinese Centre for Disease Control and Prevention, No.155 Changbai Road, Changping District, Beijing, China.
Hui-Ling WangNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, WHO WPRO Regional Reference Measles/Rubella Laboratory, Chinese Centre for Disease Control and Prevention, No.155 Changbai Road, Changping District, Beijing, China.
Zhen ZhuNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, WHO WPRO Regional Reference Measles/Rubella Laboratory, Chinese Centre for Disease Control and Prevention, No.155 Changbai Road, Changping District, Beijing, China. zhuzhen@ivdc.chinacdc.cn.
Nai-Ying MaoNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, WHO WPRO Regional Reference Measles/Rubella Laboratory, Chinese Centre for Disease Control and Prevention, No.155 Changbai Road, Changping District, Beijing, China. maony@ivdc.chinacdc.cn.

Funding

National Key R&D Program of China 2017YFC1200303National Key R&D Program of China 2022YFC2305303
6 · The paper itself

Abstract

backgroundSeroprevalence studies across various countries can contribute to achieving the elimination target for measles and rubella. However, in the Mainland of China, the concept of herd immunity remains unclear due to the lack of a nationwide serosurvey.

methodsThis systematic review and meta-analysis was conducted by retrieving literature reporting the seroprevalence of measles and rubella published between 2012 and 2023. The pooled positive rates and estimated geometric mean concentrations (GMCs) of measles and rubella immunoglobulin G antibodies were calculated.

resultsThis study analysed 135 studies on measles and 77 on rubella, including data from 368,023 and 177,422 healthy individuals, respectively. Between 2010 and 2022, the overall pooled positive rates for measles and rubella antibodies were 88.8% and 79.91%, respectively. The age-specific susceptibility analysis showed that infants aged < 1 year had the lowest pooled positive rates. Other age groups had a roughly U-shaped distribution, with relatively higher positive rates and GMC of measles and rubella antibodies in young children and older age groups. However, the positive rates for both measles and rubella antibodies fell below the elimination threshold in almost all age groups other than young children aged 1-4 years, especially in recent years. In addition, antibody positivity rates varied by geographical region and decreased with economic level.

conclusionOur findings provide preliminary insights into herd immunity for measles and rubella, highlighting the challenges to achieving their elimination in China.

Indexed as

MeaslesRubellaAntibodies, ViralChildChild, PreschoolChinaEpidemicsFemaleHumansInfantRisk AssessmentSeroepidemiologic StudiesAntibodies, ViralEliminationMeaslesMeta-analysisRubellaSeroprevalence

Identifiers

PMID39627646

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.