Evidence map›Paper›PMID 39627539›Full record

ArticleCommunications biology2024

Quantitative single-molecule analysis of assembly and Ca

Feng Li, Jeff Coleman, Lorena Redondo-Morata, R Venkat Kalyana Sundaram, Ekaterina Stroeva, James E Rothman, Frédéric Pincet

Abstract read
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Synaptic transmission: Munc13 assembles onto PI(4,5)PProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Feng LiDepartment of Cell Biology, School of Medicine, Yale University, 333 Cedar Street, New Haven, CT, 06520, USA.
Jeff ColemanDepartment of Cell Biology, School of Medicine, Yale University, 333 Cedar Street, New Haven, CT, 06520, USA.
Lorena Redondo-MorataAix-Marseille University, INSERM, DyNaMo, Turing centre for living systems, Marseille, France.ORCID 0000-0002-6254-8261
R Venkat Kalyana SundaramDepartment of Cell Biology, School of Medicine, Yale University, 333 Cedar Street, New Haven, CT, 06520, USA.
Ekaterina StroevaDepartment of Cell Biology, School of Medicine, Yale University, 333 Cedar Street, New Haven, CT, 06520, USA.
James E RothmanDepartment of Cell Biology, School of Medicine, Yale University, 333 Cedar Street, New Haven, CT, 06520, USA. james.rothman@yale.edu.
Frédéric PincetDepartment of Cell Biology, School of Medicine, Yale University, 333 Cedar Street, New Haven, CT, 06520, USA. frederic.pincet@ens.fr.ORCID 0000-0002-4243-2157

Funding

Regulation of Membrane Fusion in ExocytosisR01DK027044 · NIDDK · YALE UNIVERSITY · PI KRISHNAKUMAR, SHYAM S · 1986 to 2021
$8.2M
MECHANISMS OF INTRACELLULAR MEMBRANE FUSIONR37DK027044 · NIDDK · YALE UNIVERSITY · PI ROTHMAN, JAMES · 1992 to 2012
$5.3M
NIDDK NIH HHS R01 DK027044NIDDK NIH HHS R37 DK027044U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) DK027044
6 · The paper itself

Abstract

Synaptotagmin-1 (Syt-1) self-assembles into ring-like oligomers, and genetic and biochemical evidence suggest that oligomerization is needed to clamp synaptic vesicles and stabilize them for Ca

Indexed as

CalciumLipid BilayersSingle Molecule ImagingSynaptotagmin IAnimalsProtein MultimerizationCalciumLipid BilayersSynaptotagmin I

Identifiers

PMID39627539
PMCPMC11615320

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.