Evidence map›Paper›PMID 39627519›Full record

ArticleScientific reports2024

Association between first-trimester subchorionic hematoma and pregnancy loss before 20 weeks of gestation in singleton pregnancies.

Ying Lou, Guili Chen, Lanying Wang, Xiaoqing Zhao, Jianting Ma

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ying LouObstetrics and Gynecology Department, Yuyao People's Hospital, 800St Chengdong Road, Yuyao, 315400, Zhejiang, China.
Guili ChenObstetrics and Gynecology Department, Yuyao People's Hospital, 800St Chengdong Road, Yuyao, 315400, Zhejiang, China.
Lanying WangObstetrics and Gynecology Department, Yuyao People's Hospital, 800St Chengdong Road, Yuyao, 315400, Zhejiang, China.
Xiaoqing ZhaoObstetrics and Gynecology Department, Yuyao People's Hospital, 800St Chengdong Road, Yuyao, 315400, Zhejiang, China.
Jianting MaObstetrics and Gynecology Department, Yuyao People's Hospital, 800St Chengdong Road, Yuyao, 315400, Zhejiang, China. mjt9977@126.com.

Funding

Project for Zhejiang Medical Technology and Hygiene Program 2021KY1073
6 · The paper itself

Abstract

To evaluate the association between a first-trimester subchorionic hematoma (SCH) and pregnancy loss before 20 weeks of gestation in singleton pregnancies. We conducted a retrospective cohort study of singleton pregnancies from January to December 2021. All patients had routine first-trimester ultrasound scans and were followed up for pregnancy outcomes. We compared pregnancy loss rates before 20 weeks in women with and without SCH and analyzed risk factors using logistic regression. Out of 1,144 singleton pregnancies, 559 (48.9%) had SCH. Women with SCH had higher rates of vaginal bleeding (38.1 vs. 23.2%, P < 0.001). SCH was independently associated with miscarriage before 20 weeks (adjusted OR 1.94, 95% CI 1.19-3.15). Earlier SCH diagnosis increased miscarriage risk (adjusted OR 2.71 for diagnosis before 7 weeks, 95% CI 1.45-5.07). SCH size was not linked to pregnancy loss, but "large" SCH increased placental abruption risk (adjusted OR 5.03, 95% CI 1.20-21.11). Dydrogesterone use appeared protective against miscarriage (adjusted OR 0.28, 95% CI 0.15-0.52). First-trimester SCH is associated with an increased risk of miscarriage before 20 weeks. Large SCHs increase the risk of placental abruption, while dydrogesterone use may reduce miscarriage risk.

Indexed as

Abortion, SpontaneousHematomaPregnancy Trimester, FirstAdultChorionFemaleGestational AgeHumansPregnancyPregnancy OutcomeRetrospective StudiesRisk FactorsDydrogesteronePlacental abruptionPregnancy lossSubchorionic hematoma

Identifiers

PMID39627519
PMCPMC11615346

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.