Evidence map›Paper›PMID 39627496›Full record

Trial reportJournal of behavioral medicine2025

Adapting a pain coping skills training intervention for people with chronic pain receiving maintenance hemodialysis for end stage Kidney disease.

Jennifer L Steel, Carrie E Brintz, Alicia A Heapy, Francis Keefe, Martin D Cheatle, Manisha Jhamb, Daniel W McNeil, Amanda J Shallcross, Paul L Kimmel, Laura M Dember and 3 more

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of behavioral medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04571619 (A Randomized Clinical Trial to Evaluate Non-Pharmacologic and Pharmacologic Approaches for Reducing Pain and Opioid Use Among Patients Treated With Maintenance Hemodialysis), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04571619 phase2completednot on this map

A Randomized Clinical Trial to Evaluate Non-Pharmacologic and Pharmacologic Approaches for Reducing Pain and Opioid Use Among Patients Treated With Maintenance Hemodialysis

TypeinterventionalSponsorNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Ran2021 to 2024Enrolled643ConditionsEnd Stage Renal Disease, Chronic Pain, Opioid DependenceArmsPain Coping Skills Training (PCST), Buprenorphine
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jennifer L SteelCenter for Excellence in Behavioral Medicine, University of Pittsburgh School of Medicine, 3471 Fifth Avenue, Suite 601, Pittsburgh, PA, 15213, USA. steejl@upmc.edu.ORCID 0000-0002-1959-1854
Carrie E BrintzVanderbilt University Medical Center, Nashville, USA.
Alicia A HeapyYale School of Medicine, New Haven, USA.
Francis KeefeDuke University Medical School, Durham, USA.
Martin D CheatleUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Manisha JhambCenter for Excellence in Behavioral Medicine, University of Pittsburgh School of Medicine, 3471 Fifth Avenue, Suite 601, Pittsburgh, PA, 15213, USA.
Daniel W McNeilUniversity of Florida, Gainesville, USA.
Amanda J ShallcrossNew York University School of Medicine/Cleveland Clinic, New York, USA.
Paul L KimmelNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, USA.
Laura M DemberUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
David M WhiteAmerican Association of Kidney Patients, Tampa, USA.
Joey WilliamsHennepin County Medical Center Research Institute, Minneapolis, USA.
Daniel CukorThe Rogosin Institute, New York, USA.

Funding

UPENN Scientific and Data Research Center for the HOPE Consortium to Reduce Pain and Opioid Use in Hemodialysis U01DK123813 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI DEMBER, LAURA M, FARRAR, JOHN T · 2019 to 2024
$6.6M
Randomized ESRD Trial COmparing CBT alone VERsus with buprenorphine (RECOVER)U01DK123786 · NIDDK · UNIVERSITY OF WASHINGTON · PI CUKOR, DANIEL, MEHROTRA, RAJNISH · 2019 to 2022
$3.4M
Pain Reduction and Opioid MedIcation Safety in ESRD (PROMISE) studyU01DK123812 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JHAMB, MANISHA, LIEBSCHUTZ, JANE M · 2019 to 2020
$3.1M
University of Illinois at Chicago Hemodialysis Opioid Prescription Effort (HOPE) Clinical CenterU01DK123787 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DOORENBOS, ARDITH Z, FISCHER, MICHAEL J. · 2019 to 2020
$3.0M
Pain, Opioids, and ESRD risk reduction with Mindfulness and Buprenorphine (POEM-B): A 3-arm multi-site randomized trial in hemodialysis patientsU01DK123814 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHARYTAN, DAVID M, LEE, JOSHUA D · 2019 to 2019
$2.9M
Vanderbilt-West Virginia (VWV) Collaborative: A HOPE Consortium Clinical CenterU01DK123821 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CAVANAUGH, KERRI · 2019 to 2019
$2.9M
The Hemodialysis Opioid Prescription Effort ConsortiumU01DK123816 · NIDDK · HENNEPIN HEALTHCARE RESEARCH INSTITUTE · PI BART, GAVIN, JOHANSEN, KIRSTEN L. · 2019 to 2019
$2.6M
Video-Telecare Collaborative Pain Management to Improve Function and Reduce Opioid Risk in Patients with End Stage Renal Disease Receiving HemodialysisU01DK123817 · NIDDK · YALE UNIVERSITY · PI BECKER, WILLIAM C, CROWLEY, SUSAN T · 2019 to 2019
$2.6M
Reducing Chronic Pain and Opioid Use in Hemodialysis PatientsU01DK123818 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI KALIM, SAHIR, NIGWEKAR, SAGAR · 2019 to 2019
$2.4M
NIDDK NIH HHS U01 DK123786NIDDK NIH HHS U01DK123786NIDDK NIH HHS U01 DK123787NIDDK NIH HHS U01DK123787NIDDK NIH HHS U01 DK123812NIDDK NIH HHS U01DK123812NIDDK NIH HHS U01 DK123813NIDDK NIH HHS U01DK123813NIDDK NIH HHS U01 DK123814NIDDK NIH HHS U01DK123814NIDDK NIH HHS U01 DK123816NIDDK NIH HHS U01DK123816NIDDK NIH HHS U01 DK123817NIDDK NIH HHS U01DK123817NIDDK NIH HHS U01 DK123818NIDDK NIH HHS U01DK123818NIDDK NIH HHS U01 DK123821NIDDK NIH HHS U01DK123821
6 · The paper itself

Abstract

Pain Coping Skills Training (PCST) is a first-line cognitive-behavioral, non-pharmacological treatment for chronic pain and comorbid symptoms. PCST has been shown to be effective in racially and ethnically diverse cohorts across several chronic medical conditions. However, PCST has not been evaluated in those with end stage kidney disease (ESKD) receiving in-center maintenance hemodialysis. Due to the high rates of morbidity associated with ESKD, and time-intensive treatment, an adaptation of PCST was warranted to address the unique challenges experienced by people living with ESKD. Using current guidelines developed by Card and colleagues for intervention adaptation, PCST was adapted so that it could be implemented among people living with ESKD in a national multisite trial. The objective of this paper was to describe the adaption process outlined by Card and colleagues including how the team selected an effective intervention to adapt, developed a program model, identified mismatches in the original intervention and study population, and then adapted the intervention for those with ESKD treated with in-center maintenance hemodialysis. Finally, we briefly describe future directions for clinical practice and research with the adapted PCST intervention for those with ESKD.Trial registration: ClinicalTrials.gov #NCT04571619.

Indexed as

Adaptation, PsychologicalChronic PainCognitive Behavioral TherapyKidney Failure, ChronicPain ManagementRenal DialysisCoping SkillsFemaleHumansMaleEnd stage kidney diseaseHemodialysisPainPain coping and skills training

Identifiers

PMID39627496
PMCPMC12512601

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.