Evidence map›Paper›PMID 39627456›Full record

Trial reportEuropean journal of clinical nutrition2025

Effect of sorghum flour-containing pasta on postprandial glycemia, appetite and energy intake in healthy individuals.

Imran Khan, Stuart K Johnson, Adel M Yousif, Shirani Gamlath, Jamil Ahmad, Ali Madi Almajwal

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Imran KhanDepartment of Food Science and Nutrition, College of Agricultural and Marine Sciences, Sultan Qaboos University, Al-Khoud 123, Muscat, Oman. i.khan1@squ.edu.om.ORCID http://orcid.org/0009-0009-7148-9839
Stuart K JohnsonFood Science and Technology Program, School of Public Health, Faculty of Health Sciences, Curtin University, Perth, WA, 6845, Australia. S.Johnson@curtin.edu.au.ORCID http://orcid.org/0000-0001-8357-797X
Adel M YousifTasmanian Institute of Agriculture, University of Tasmania, Sandy Bay, TAS, 7001, Australia.ORCID http://orcid.org/0000-0002-1751-7888
Shirani GamlathCASS Food Research Centre, School of Exercise and Nutrition Sciences, Deakin University, Burwood, NSW, 3125, Australia.ORCID http://orcid.org/0000-0002-2053-2624
Jamil AhmadDepartment of Human Nutrition, The University of Agriculture, Peshawar, Khyber Pakhtunkhwa, 25130, Pakistan.ORCID http://orcid.org/0000-0001-6935-215X
Ali Madi AlmajwalDepartment of Community Health Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia.

Funding

KSU | Deanship of Scientific Research, King Saud University (Deanship of Scientific Research) RSP2024R502
6 · The paper itself

Abstract

BACKGROUND/

objectivesIn vitro studies suggest that incorporating sorghum flour into staple foods including pasta reduces their starch digestibility and hence may suppress postprandial blood glucose levels, appetite and energy intake; however, these effects in humans have yet to be reported. Therefore, this study investigated the effect of red and white sorghum-containing pasta on blood glucose response, appetite and energy intake in humans. SUBJECTS/

methodsIn a randomised crossover design, healthy individuals (n = 20) consumed the following three iso-caloric test meals (each providing 50 g available carbohydrates) as breakfast: control pasta (CP) made from100% durum wheat; 30% red sorghum pasta (RSP) and; 30% white sorghum pasta (WSP). Blood glucose and subjective appetite were measured postprandially for 2 and 3 h, respectively. Energy intakes from ad libitum lunch consumed 3 h after breakfast and for the remainder of the day were also measured. Incremental areas under or over the curves (iAUCs/iAOCs) for blood glucose and appetite parameters were calculated.

resultsThe RSP meal resulted in significantly lower blood glucose response (-0.35 ± 0.09 mmol/l; 95% CI: -0.61 ~ -0.09; P = 0.005) and glucose iAUC over 120 min (-36.11 ± 10.53 mmol/l × min; 95% CI: -67.11 ~ -5.11; P = 0.017) compared to CP meal. Compared to CP meal, the RSP meal resulted in significantly higher satiety iAUC (1219.46 ± 383.26 mm × min; 95% 91.18 ~ 2347.75; P = 0.029), lower hunger iAOC (-1410.47 ± 349.14 mm x min; 95% CI: -2438.30 ~ -382.63; P = 0.004) and lower prospective food intake iAOC (-1645.73 ± 324.14 mm x min; 95% CI: -2599.97 ~ -691.49; P < 0.001). Energy intake at ad libitum lunch was significantly lower after the RSP meal than after the CP meal (-794.17 ± 163.25 kJ; 95% CI: -1274.77 ~ -313.57; P = 0.001).

conclusionThe results indicate that red sorghum addition into pasta provides a product inducing reduced glycemia, favourably changed appetite parameters and decreased subsequent energy intake.

Indexed as

AppetiteBlood GlucoseEnergy IntakeFlourPostprandial PeriodSorghumAdultBreakfastCross-Over StudiesFemaleHumansMaleTriticumYoung AdultBlood Glucose

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.