Evidence map›Paper›PMID 39627334›Full record

ArticleAesthetic plastic surgery2025

3D Assessment of Mandibular Margin Morphological Change after BTX-A Injection for Masseter Hypertrophy: A Retrospective Study.

Siqi Zhang, Hongli Zhao, Chang Liu, Xiang Gao, Lijun Hao

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Article in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Siqi ZhangThe Plastic and Aesthetic Center, The First Affiliated Hospital of Harbin Medical University, No. 23 Youzheng Street, Nangang District, Harbin, 150000, Heilongjiang, P. R. China.
Hongli ZhaoDepartment of Plastic and Aesthetic (Burn) Surgery, The Second Xiangya Hospital of Central South University, Changsha City, Hunan Province, P. R. China.
Chang LiuThe Plastic and Aesthetic Center, The First Affiliated Hospital of Harbin Medical University, No. 23 Youzheng Street, Nangang District, Harbin, 150000, Heilongjiang, P. R. China.
Xiang GaoThe Plastic and Aesthetic Center, The First Affiliated Hospital of Harbin Medical University, No. 23 Youzheng Street, Nangang District, Harbin, 150000, Heilongjiang, P. R. China.
Lijun HaoThe Plastic and Aesthetic Center, The First Affiliated Hospital of Harbin Medical University, No. 23 Youzheng Street, Nangang District, Harbin, 150000, Heilongjiang, P. R. China. haolijundoctor@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSome facial morphological changes may occur in some patients after botulinum toxin A (BTX-A) injection for the treatment of masseteric hypertrophy. The aim of this study was to investigate the morphological changes that occurred on mandibular margin.

methodsThis retrospective analysis included 43 patients (86 lateral cases) who received BTX-A injections for masseter hypertrophy. To assess the morphological changes in the mandibular margin after treatment, the sharpness of the mandibular margin was evaluated before and after the injections using an established grading system. Additionally, 3D scanning technology was used to measure both the therapeutic effect of the BTX-A injections and the extent of soft tissue sagging in the mandibular margin area.

resultsGrading: The grade of mandibular margin sharpness change occurred in 41 lateral cases post-procedurally. EVALUATION: Based on the measurement results, statistically significant differences were observed before, 1 month, and 3 months post-procedurally in subjects' positive lower face width representing the therapeutic effect of BTX-A injection and the extent of sagging soft tissue at sagittal section B and section C (p < 0.05), but not in section A (A: outer canthus, B: midpoint of the eyelid margin, and C: inner canthus) (p > 0.05).

conclusionAfter receiving a BTX-A injection for masseteric hypertrophy, the mandibular margin may develop an unclear mandibular margin and sagging soft tissue in mandibular margin area. EBM Level: IV LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

Indexed as

Botulinum Toxins, Type AHypertrophyImaging, Three-DimensionalMandibleMasseter MuscleNeuromuscular AgentsAdultFemaleFollow-Up StudiesHumansInjections, IntramuscularMaleMiddle AgedRetrospective StudiesTreatment OutcomeYoung AdultBotulinum Toxins, Type ANeuromuscular AgentsBotulinum toxin ALower face contourMandibular marginMasseteric hypertrophy

Identifiers

PMID39627334

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.