Evidence map›Paper›PMID 39627292›Full record

ArticleScientific reports2024

Endoscopic transsphenoidal surgery for infradiaphragmatic craniopharyngiomas and impact of diaphragm sellae competence on hypothalamic injury.

Xuan Gong, Zhou Chen, Kui Yang, Chuntao Li, Songshan Feng, Mingyu Zhang, Zhixiong Liu, Hongshu Zhou, Zhenyan Li

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Xuan GongDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Zhou ChenDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Kui YangDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Chuntao LiDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Songshan FengDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Mingyu ZhangDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Zhixiong LiuDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Hongshu ZhouDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China. zhou_hs@csu.edu.cn.
Zhenyan LiDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China. lizhenyan@csu.edu.cn.

Funding

Natural Science Foundation of Hunan Province 2018JJ3824the National Natural Science Foundation of China 81701285
6 · The paper itself

Abstract

Investigate the impact of diaphragm sellae competence on surgical outcomes and risk factors for postoperative hypothalamic injury (HI) in patients undergoing endoscopic transsphenoidal surgery (ETS) for infradiaphragmatic craniopharyngiomas (ICs). A retrospective analysis of 54 consecutive patients (2016-2023) with ICs treated by ETS was conducted. All tumors originated from the sellar region inferior to the diaphragm sellae and were classified into two subtypes in terms of diaphragm sellae competence: IC with competent diaphragm sellae (IC-CDS) and IC with incompetent diaphragm sellae (IC-IDS). Clinical features, intraoperative findings, and follow-up data were compared between subtypes. Postoperative HI was assessed using an magnetic resonance imaging-based scoring system. Fifty-four patients (29 males, 25 females) were included in this study, with 12 (22.2%) under 18 years old. Overall, 35 cases were IC-CDS, while 19 were IC-IDS. Compared with IC-CDS, patients with IC-IDS tended to have hormone hypofunction before surgery (p = 0.03). Tumor volume in IC-IDS group (9.0 ± 8.6 cm

Indexed as

CraniopharyngiomaHypothalamusPituitary NeoplasmsPostoperative ComplicationsAdolescentAdultAgedChildDiaphragmEndoscopyFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesComplicationCraniopharyngiomaEndoscopic transsphenoidal surgeryHypothalamic injuryInfradiaphragmaticSubtype

Identifiers

PMID39627292
PMCPMC11615359

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.