ArticleNature communications2024
An anticoagulant supercapacitor for implantable applications.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
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- Nasal-to-Brain ROS-Responsive Diselenide-Bridged Graphene Nanogel for Targeted Ischemic Stroke Therapy via Microglial Modulation.ACS omega · 2026Article
- Wearable Battery-Free Electrotherapy of Smartsensors for Wound Healthcare.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Four-dimensional reconfigurable vascular tunneling machine of spatially programmed liquid crystal elastomers.Nature communications · 2026Article
- Dendritic Nano-Based Slippery Coating by Synergistic Mechanical and Electrostatic Interactions with Persistent and Exceptional Combats Thrombosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Robust adhesive, antibacterial, pro-angiogenic and osteogenic bone adhesives with moderate degradability facilitating bone regeneration.Bioactive materials · 2026Article
- Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Concrete Structure Inspired 3D-Printed Framework Mechanically Reinforced Zwitterionic Hydrogel for Efficient Postoperative Abdominal Adhesion Prevention.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Bidirectional mechanisms and emerging strategies for implantable bioelectronic interfaces.Bioactive materials · 2025Review
- From reactive to proactive: Continuous protein monitoring for preventive health care.Science (New York, N.Y.) · 2025Review
- Fully biocompatible, thermally drawn fiber supercapacitors for long-term bio-implantation.Nature communications · 2025Article
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Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With the rapid advancement of implantable electronic medical devices, implantable supercapacitors have emerged as popular energy storage devices. However, supercapacitors inevitably come into direct contact with blood when implanted, potentially causing adverse clinical reactions such as coagulation and thrombosis, impairing the performance of implanted energy storage devices, and posing a serious threat to human health. Therefore, this work aims to design an anticoagulant supercapacitor by heparin doped poly(3, 4-ethylenedioxythiophene) (PEDOT) for possible applications in implantable bioelectronics. Heparin (Hep), the as-known anticoagulant macromolecule acts as the counterion for PEDOT doping to enhance its conductivity, and the bioelectrode material PEDOT: Hep with anticoagulant activity is synthesized via chemical oxidation polymerization. Concurrently, the anticoagulant supercapacitor is constructed through in-situ polymerization, where PEDOT: Hep and bacterial cellulose as electrode material and electrolyte layer, respectively. Owing to the incorporation of heparin, the supercapacitor exhibits high hemocompatibility with hemolysis rate <5 %, good anticoagulant performance with coagulation time of 63.4 s, reasonable cycle stability with capacitance retention rate of 76.24 % after 20, 000 cycles, and supplies power for implanted heart rate sensors in female mice. This work provides a platform for implantable electronics to achieve anticoagulant activity in vivo.
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