Evidence map›Paper›PMID 39627169›Full record

ReviewOperative neurosurgery (Hagerstown, Md.)2025

A General Framework for Characterizing Inaccuracy in Stereotactic Systems.

Michael A Jensen, Joseph S Neimat, Panagiotis Kerezoudis, Rushna Ali, R Mark Richardson, Casey H Halpern, Steven Ojemann, Francisco A Ponce, Kendall H Lee, Laura M Haugen and 3 more

Abstract readReview
In one paragraph

Review in Operative neurosurgery (Hagerstown, Md.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. A Pneumatically Actuated Robotic Assistant for MRI-Guided Stereotactic Neurosurgery.IEEE transactions on medical robotics and bionics · 2026
    Article
  4. Article
  5. Article
  6. Principles of Stereotactic Surgery.Operative neurosurgery (Hagerstown, Md.) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Michael A JensenDepartment of Neurologic Surgery, Mayo Clinic, Rochester , Minnesota , USA.ORCID 0000-0002-5191-7244
Joseph S NeimatDepartment of Neurosurgery, University of Louisville, Louisville , Kentucky , USA.ORCID 0000-0002-1114-8938
Panagiotis KerezoudisDepartment of Neurologic Surgery, Mayo Clinic, Rochester , Minnesota , USA.
Rushna AliDepartment of Neurologic Surgery, Mayo Clinic, Rochester , Minnesota , USA.
R Mark RichardsonDepartment of Neurosurgery, Massachusetts General Hospital, Boston , Massachusetts , USA.
Casey H HalpernDepartment of Neurosurgery, University of Pennsylvania, Philadelphia , Pennsylvania , USA.
Steven OjemannDepartment of Neurosurgery, University of Colorado Health Neurosciences Center, Denver , Colorado , USA.
Francisco A PonceDepartment of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix , Arizona , USA.
Kendall H LeeDepartment of Neurologic Surgery, Mayo Clinic, Rochester , Minnesota , USA.
Laura M HaugenDepartment of Neurologic Surgery, Mayo Clinic, Rochester , Minnesota , USA.
Bryan T KlassenDepartment of Neurology, Mayo Clinic, Rochester , Minnesota , USA.
Douglas KondziolkaDepartment of Neurosurgery, NYU Langone Health, New York , New York , USA.ORCID 0000-0001-8925-7344
Kai J MillerDepartment of Neurologic Surgery, Mayo Clinic, Rochester , Minnesota , USA.ORCID 0000-0002-6687-6422

Funding

MSTP at Mayo Clinic RochesterT32GM145408 · NIGMS · MAYO CLINIC ROCHESTER · PI SCOTT H KAUFMANN, LISA A SCHIMMENTI · 2023 to 2026
$4.7M
An Ecosystem of Technology and Protocols for Adaptive Neuromodulation Research in HumansU01NS128612 · NINDS · MAYO CLINIC ROCHESTER · PI Peter Brunner, Kai Miller · 2022 to 2026
$4.5M
Quantifying the Interdependence of the Motor Network Using Intracranial ElectrodesF31NS135898 · NINDS · MAYO CLINIC ROCHESTER · PI JENSEN, MICHAEL A · 2024 to 2024
$49k
NIGMS NIH HHS T32 GM145408NINDS NIH HHS F31 NS135898NINDS NIH HHS U01 NS128612
6 · The paper itself

Abstract

BACKGROUND AND

objectivesIdentifying and characterizing sources of targeting error in stereotactic procedures is essential to maximizing accuracy, potentially improving surgical outcomes. We aim to describe a generic framework which characterizes sources of stereotactic inaccuracy.

methodsWe assembled a list of stereotactic systems: ROSA, Neuromate, Mazor Renaissance, ExcelsiusGPS, Cirq, STarFix (FHC), Nexframe, ClearPoint, CRW, and Leksell. We searched the literature for qualitative and quantitative work identifying and quantifying potential sources of inaccuracy and describing each system's implementation using Standards for Reporting Qualitative Research guidelines. Our literature search spanned 1969 to 2024, and various studies were included, with formats ranging from phantom studies to systematic reviews. Keyword searches were conducted, and the details about each system were used to create a framework for identifying and describing the unique targeting error profile of each system.

resultsWe describe and illustrate the details of various sources of stereotactic inaccuracies and generate a framework to unify these sources into a single framework. This framework entails 5 domains: imaging, registration, mechanical accuracy, target planning and adjustment, and trajectory planning and adjustment. This framework was applied to 10 stereotactic systems.

conclusionThis framework provides a rubric to analyze the sources of error for any stereotactic system. Illustrations allow the reader to understand sources of error conceptually so that they may apply them to their practice.

Indexed as

Medical ErrorsStereotaxic TechniquesHumans

Identifiers

PMID39627169
PMCPMC11809961

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.