Evidence map›Paper›PMID 39626964›Full record

ArticleLife science alliance2025

Hypoxia favors tumor growth in colorectal cancer in an integrin αDβ1/hemoglobin δ-dependent manner.

Erkki Koivunen, Sudarrshan Madhavan, Laura Bermudez Garrido, Mikaela Grönholm, Tuomas Kaprio, Caj Haglund, Leif C Andersson, Carl G Gahmberg

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life science alliance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Erkki KoivunenProgramme in Molecular and Integrative Biosciences, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-6443-9595
Sudarrshan MadhavanProgramme in Molecular and Integrative Biosciences, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-1084-9919
Laura Bermudez GarridoProgramme in Molecular and Integrative Biosciences, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.ORCID 0009-0003-3140-2504
Mikaela GrönholmDrug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-2378-8924
Tuomas KaprioProgramme in Translational Cancer Medicine, Faculty of Medicine, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-0377-9975
Caj HaglundProgramme in Translational Cancer Medicine, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Leif C AnderssonDepartment of Pathology. Faculty of Medicine, University of Helsinki, Helsinki, Finland.ORCID 0000-0001-6264-9620
Carl G GahmbergProgramme in Molecular and Integrative Biosciences, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland carl.gahmberg@helsinki.fi.ORCID 0000-0001-9892-9296

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low oxygen tension (PO

Indexed as

Cell ProliferationColorectal NeoplasmsCell AdhesionCell HypoxiaCell Line, TumorHumansHypoxiaOxygenOxygen

Identifiers

PMID39626964
PMCPMC11629678

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.