Evidence map›Paper›PMID 39626654›Full record

ReviewClinical & experimental ophthalmology2024

Mimickers of hydroxychloroquine retinal toxicity.

Peter Jones, Gagan Kalra, Mayss Al-Sheikh, Jay Chhablani

Abstract readReview
In one paragraph

Review in Clinical & experimental ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Mimickers of hydroxychloroquine retinal toxicity.Clinical & experimental ophthalmology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Peter JonesUPMC Vision Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Gagan KalraUPMC Vision Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-3367-3047
Mayss Al-SheikhUniversity Hospital Zurich, University of Zurich, Zurich, Switzerland.
Jay ChhablaniUPMC Vision Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydroxychloroquine (HCQ) retinal toxicity is an important entity that can be challenging to differentiate from its mimickers. Bull's eye maculopathy is the classical presentation of HCQ retinopathy; however, its differential includes several drug-related retinal toxicities, inherited retinal disorders, and systemic conditions with associated retinopathies. Given the similarities in clinical presentation, imaging findings, and other diagnostic data, it can be quite challenging for all but the retina specialists to successfully identify retinal toxicity from HCQ. This review summarises HCQ retinopathy and its mimickers of with a special emphasis on key clinical and ancillary distinctions that can help comprehensive ophthalmologists and primary care offices in clenching this diagnosis.

Indexed as

Antirheumatic AgentsHydroxychloroquineRetinal DiseasesDiagnosis, DifferentialFluorescein AngiographyHumansRetinaTomography, Optical CoherenceAntirheumatic AgentsHydroxychloroquinebulls eye maculopathyhydroxychloroquine retinal toxicityhydroxychloroquine retinopathy mimickersinherited retinal degenerationsplaquenil toxicity

Identifiers

PMID39626654
PMCPMC11620849

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.