Evidence map›Paper›PMID 39626311›Full record

ArticleBioinformatics (Oxford, England)2024

spread.gl: visualizing pathogen dispersal in a high-performance browser application.

Yimin Li, Nena Bollen, Samuel L Hong, Marius Brusselmans, Fabiana Gambaro, Joon Klaps, Marc A Suchard, Andrew Rambaut, Philippe Lemey, Simon Dellicour and 1 more

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Yimin LiDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven 3000, Belgium.ORCID 0009-0007-9939-8192
Nena BollenDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven 3000, Belgium.ORCID 0000-0002-0532-0658
Samuel L HongDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven 3000, Belgium.ORCID 0000-0001-6354-4943
Marius BrusselmansDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven 3000, Belgium.ORCID 0009-0000-2134-1515
Fabiana GambaroSpatial Epidemiology Lab (SpELL), Université Libre de Bruxelles, Brussels 1050, Belgium.ORCID 0000-0001-7760-2112
Joon KlapsDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven 3000, Belgium.ORCID 0000-0002-2507-0430
Marc A SuchardDepartment of Biomathematics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, United States.ORCID 0000-0001-9818-479X
Andrew RambautInstitute of Ecology and Evolution, University of Edinburgh, Edinburgh, EH9 3FL, United Kingdom.ORCID 0000-0003-4337-3707
Philippe LemeyDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven 3000, Belgium.ORCID 0000-0003-2826-5353
Simon DellicourDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven 3000, Belgium.ORCID 0000-0001-9558-1052
Guy BaeleDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven 3000, Belgium.ORCID 0000-0002-1915-7732

Funding

European Union Horizon 2020 project MOOD 874850Research Foundation - Flanders
6 · The paper itself

Abstract

motivationBayesian phylogeographic analyses are pivotal in reconstructing the spatio-temporal dispersal histories of pathogens. However, interpreting the complex outcomes of phylogeographic reconstructions requires sophisticated visualization tools.

resultsTo meet this challenge, we developed spread.gl, an open-source, feature-rich browser application offering a smooth and intuitive visualization tool for both discrete and continuous phylogeographic inferences, including the animation of pathogen geographic dispersal through time. Spread.gl can render and combine the visualization of multiple layers that contain information extracted from the input phylogeny and diverse environmental data layers, enabling researchers to explore which environmental factors may have impacted pathogen dispersal patterns before conducting formal testing. We showcase the visualization features of spread.gl with representative examples, including the smooth animation of a phylogeographic reconstruction based on >17 000 SARS-CoV-2 genomic sequences. AVAILABILITY AND IMPLEMENTATION: Source code, installation instructions, example input data, and outputs of spread.gl are accessible at https://github.com/GuyBaele/SpreadGL.

Indexed as

PhylogeographySARS-CoV-2SoftwareBayes TheoremCOVID-19HumansPhylogenyWeb Browser

Identifiers

PMID39626311
PMCPMC11652268

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.