Evidence map›Paper›PMID 39625881›Full record

ArticlePloS one2024

MetaCONNET: A metagenomic polishing tool for long-read assemblies.

Bingru Sun, Jian Guo, Hao Jin, Zijie Jin, Yaping Sun, Yuanchen Mao, Fuli Xie, Yun He, Zhihong Sun, Wei Li and 2 more

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Systematic Review: Long-Read Sequencing in Algal Studies.International journal of molecular sciences · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bingru SunAxbio Biotechnology (Shenzhen) Co., Ltd., Shenzhen, China.
Jian GuoAxbio Biotechnology (Shenzhen) Co., Ltd., Shenzhen, China.ORCID 0000-0002-0314-4080
Hao JinKey Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Inner Mongolia Agricultural University, Hohhot, China.
Zijie JinPeking University International Cancer Institute, Health Science Center, Peking University, Beijing, China.
Yaping SunAxbio Biotechnology (Shenzhen) Co., Ltd., Shenzhen, China.
Yuanchen MaoAxbio Biotechnology (Shenzhen) Co., Ltd., Shenzhen, China.
Fuli XieAxbio Biotechnology (Shenzhen) Co., Ltd., Shenzhen, China.
Yun HeAxbio Biotechnology (Shenzhen) Co., Ltd., Shenzhen, China.
Zhihong SunKey Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Inner Mongolia Agricultural University, Hohhot, China.
Wei LiAxbio Biotechnology (Shenzhen) Co., Ltd., Shenzhen, China.ORCID 0000-0003-4475-531X
Igor IvanovAxbio Biotechnology (Shenzhen) Co., Ltd., Shenzhen, China.
Hui TianAxbio Biotechnology (Shenzhen) Co., Ltd., Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate and high coverage genome assemblies are the basis for downstream analysis of metagenomic studies. Long-read sequencing technology is an ideal tool to facilitate the assemblies of metagenome, except for the drawback of usually producing reads with high sequencing error rate. Many polishing tools were developed to correct the sequencing error, but most are designed on the ground of one or two species. Considering the complexity and uneven depth of metagenomic study, we present a novel deep-learning polishing tool named MetaCONNET for polishing metagenomic assemblies. We evaluate MetaCONNET against Medaka, CONNET and NextPolish in accuracy, coverage, contiguity and resource consumption. Our results demonstrate that MetaCONNET provides a valuable polishing tool and can be applied to many metagenomic studies.

Indexed as

MetagenomeMetagenomicsAnimalsDeep LearningHigh-Throughput Nucleotide SequencingSequence Analysis, DNASoftware

Identifiers

PMID39625881
PMCPMC11614293

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.