Evidence map›Paper›PMID 39625829›Full record

ArticleAngewandte Chemie (International ed. in English)2025

Monodisperse Chemical Oligophosphorylation of Peptides via Protected Oligophosphorimidazolide Reagents.

Kevin Qian, Björn Hanf, Christopher Cummins, Dorothea Fiedler

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Synthesis of Diaryl- and Dialkynylphosphinates From Ubiquitous PAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kevin QianDepartment of Chemistry, Massachusetts Institute of Technology (MIT), 77 Massachusetts Ave., Cambridge, MA-02139, United States of America.ORCID 0000-0003-3288-0973
Björn HanfLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Rössle-Str. 10, 13125, Berlin, Germany.ORCID 0000-0003-3291-7203
Christopher CumminsDepartment of Chemistry, Massachusetts Institute of Technology (MIT), 77 Massachusetts Ave., Cambridge, MA-02139, United States of America.ORCID 0000-0003-2568-3269
Dorothea FiedlerLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Rössle-Str. 10, 13125, Berlin, Germany.ORCID 0000-0002-0798-946X

Funding

Reagents for Chemical Oligophosphorylation, Synthesis of Oligophosphate-Organic Molecule Conjugates, and Biochemical StudiesR01GM130936 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI CUMMINS, CHRISTOPHER C · 2020 to 2023
$1.2M
Foundation for the National Institutes of Health R01GM130936NIGMS NIH HHS R01 GM130936Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung CRSII5_209412
6 · The paper itself

Abstract

Protein poly- and oligophosphorylation are recently discovered post-translational modifications that remain poorly characterized due to (1) the difficulty of extracting endogenously polyphosphorylated species without degradation and (2) the absence of synthetic and analytical tools to prepare and characterize poly- and oligophosphorylated species in biochemical contexts. Herein, we report a methodology for the selective oligophosphorylation of peptides with monodisperse phosphate chain lengths (P

Indexed as

ImidazolesPeptidesPhosphopeptidesIndicators and ReagentsPhosphorylationImidazolesIndicators and ReagentsPeptidesPhosphopeptidesAnionsPeptides and ProteinsPhosphorylationPost-translational ModificationsReagents

Identifiers

PMID39625829
PMCPMC11891630

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.