Evidence map›Paper›PMID 39625710›Full record

ArticleClinical toxicology (Philadelphia, Pa.)2025

Development of squamous cell carcinoma at the bite sites several years following suspected cobra (

Subramanian Senthilkumaran, José R Almeida, Jarred Williams, Harry F Williams, Ponniah Thirumalaikolundusubramanian, Sakthivel Vaiyapuri

Abstract readCase Reports
In one paragraph

Article in Clinical toxicology (Philadelphia, Pa.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Subramanian SenthilkumaranManian Medical Centre, Erode, Tamil Nadu, India.
José R AlmeidaSchool of Pharmacy, University of Reading, Reading, UK.
Jarred WilliamsSchool of Pharmacy, University of Reading, Reading, UK.
Harry F WilliamsToxiven Biotech Private Limited, Coimbatore, Tamil Nadu, India.
Ponniah ThirumalaikolundusubramanianThe Tamil Nadu Dr M.G.R Medical University, Chennai, Tamil Nadu, India.
Sakthivel VaiyapuriSchool of Pharmacy, University of Reading, Reading, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSnakebite envenoming is a multidimensional issue that causes severe functional and life-challenging consequences among rural communities in tropical countries. Current research and treatments are largely focused on the acute effects of envenomation and short-term health outcomes. The knowledge of snakebite-induced long-term consequences is highly limited. CASE SERIES: We report the development of squamous cell carcinoma at the bite site several years later in four patients who are suspected to have been bitten by cobras ( DISCUSSION: These patients highlight the importance of squamous cell carcinoma in previously damaged tissue from snakebites as a possible long-term consequence. This emphasises the need for surveillance systems focused on a broad range of snakebite-induced consequences including long-term pathological, psychological, and socioeconomic conditions.

conclusionThis case series describes pathological complications following cobra bites that require further research to determine mechanistic and epidemiological insights in the most affected regions by snakebites, specifically in India.

Indexed as

Carcinoma, Squamous CellElapid VenomsNaja najaSkin NeoplasmsSnake BitesAnimalsHumansElapid VenomsCancercobralong-term complicationsNaja najasnakebite envenomingvenom

Identifiers

PMID39625710
PMCPMC11854041

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.