Evidence map›Paper›PMID 39625684›Full record

ArticleBrain topography2024

Distinctive Neural Substrates of low and high Risky Decision Making: Evidence from the Balloon Analog Risk Task.

Zhenlan Jin, Simeng Li, Changan Wang, Xiaoqian Chai, Junjun Zhang, Ling Li

Abstract read
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Article in Brain topography, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Zhenlan JinMOE Key Lab for Neuroinformation, The Clinical Hospital of Chengdu Brain Science Institute, University of Electronic Science and Technology of China, Chengdu, China. jinzl@uestc.edu.cn.
Simeng LiMOE Key Lab for Neuroinformation, The Clinical Hospital of Chengdu Brain Science Institute, University of Electronic Science and Technology of China, Chengdu, China.
Changan WangMOE Key Lab for Neuroinformation, The Clinical Hospital of Chengdu Brain Science Institute, University of Electronic Science and Technology of China, Chengdu, China.
Xiaoqian ChaiDepartment of Neurology and Neurosurgery, McGill University, Montreal, QC, H3A 2B4, Canada.
Junjun ZhangMOE Key Lab for Neuroinformation, The Clinical Hospital of Chengdu Brain Science Institute, University of Electronic Science and Technology of China, Chengdu, China.
Ling LiMOE Key Lab for Neuroinformation, The Clinical Hospital of Chengdu Brain Science Institute, University of Electronic Science and Technology of China, Chengdu, China. liling@uestc.edu.cn.

Funding

Brain Canada, Healthy Brain Healthy Lives (HBHL) and the Canada Research Chairs program NSERC DGFundamental Research Funds for the Central Universities ZYGX2020FRJH014Higher Education Discipline Innovation Project B12027National Natural Science Foundation of China 62176045Sichuan Science and Technology Program 2024YFHZ0061
6 · The paper itself

Abstract

Human beings exhibit varying risk-taking behaviors in response to different risk levels. Despite numerous studies on risk-taking in decision-making, the neural mechanisms of decision-making regarding risk levels remains unclear. To investigate the neural correlates of individual differences in risk-taking under different risk-levels, we analyzed behavioral data of the Balloon Analogue Risk Task (BART) and resting-state functional Magnetic Resonance Imaging (rs-fMRI) data of healthy participants (22-39 years, N = 93) from the University of California, Los Angeles Consortium for Neuropsychiatric Phenomics dataset. In the BART, the participants decided to pump for more points or stop pumping to avoid explosion of the balloons, where the risk level was manipulated by the explosion likelihood which was distinguished by the balloon color (blue for low-, red for high- risk condition). Compared with low-risk condition, the participants pumped less number, exploded more balloons, and showed more variability in pump numbers in high-risk condition, demonstrating the effective manipulation of the risky level. Next, resting state features and functional connectivity (rsFC) strength were associated with behavioral measures in low- and high-risk conditions. We found that the explosion number of balloons were correlated with the low frequency fluctuations (ALFF) in the left dorsolateral prefrontal cortex (L. DLPFC), the rsFC strength between L. DLPFC and the left anterior orbital gyrus in the low-risk condition. In the high-risk condition, we found variability in pump numbers was correlated with the ALFF in the left middle/superior frontal gyrus, the fractional ALFF (fALFF) in the medial segment of precentral gyrus (M. PrG), and the rsFC strength between the M. PrG and bilateral precentral gyrus. Our results highlighted significance of the L. DLPFC in lower risky decision making and the precentral gyrus in higher risky decision making, suggesting that distinctive neural correlates underlie the individual differences of decision-making under different risk level.

Indexed as

Decision MakingMagnetic Resonance ImagingRisk-TakingAdultBrainBrain MappingFemaleHumansIndividualityMalePrefrontal CortexYoung AdultALFFBARTfALFFFunctional connectivityRisky decision makingRisky level

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