Evidence map›Paper›PMID 39625289›Full record

ArticleEuropean journal of neurology2025

Dysphagia increases the risk of post-stroke fatigue.

Anel Karisik, Kurt Moelgg, Lucie Buergi, Lukas Scherer, Theresa Schneider, Benjamin Dejakum, Silvia Komarek, Christian Boehme, Thomas Toell, Raimund Pechlaner and 9 more

Abstract read
In one paragraph

Article in European journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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  8. Dysphagia increases the risk of post-stroke fatigue.European journal of neurology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Anel KarisikVASCage-Centre on Clinical Stroke Research, Innsbruck, Austria.ORCID 0009-0000-3075-5437
Kurt MoelggVASCage-Centre on Clinical Stroke Research, Innsbruck, Austria.
Lucie BuergiVASCage-Centre on Clinical Stroke Research, Innsbruck, Austria.
Lukas SchererVASCage-Centre on Clinical Stroke Research, Innsbruck, Austria.
Theresa SchneiderDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Benjamin DejakumDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Silvia KomarekDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0009-0009-0805-1519
Christian BoehmeDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Thomas ToellDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0002-8168-2837
Raimund PechlanerDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Simon SollerederVASCage-Centre on Clinical Stroke Research, Innsbruck, Austria.
Sonja RossiDepartment for Hearing, Speech and Voice Disorders, ICONE-Innsbruck Cognitive Neuroscience, Medical University of Innsbruck, Innsbruck, Austria.
Michael Thomas EllerDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0009-0000-9986-8392
Gudrun SchoenherrDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Wilfried LangVASCage-Centre on Clinical Stroke Research, Innsbruck, Austria.
Stefan KiechlVASCage-Centre on Clinical Stroke Research, Innsbruck, Austria.
Michael KnoflachVASCage-Centre on Clinical Stroke Research, Innsbruck, Austria.
Lukas Mayer-SuessDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0002-2856-0101
STROKE‐CARD study group

Funding

VASCage - Centre on Clinical Stroke Research 898252
6 · The paper itself

Abstract

backgroundPost-stroke dysphagia is known to have a pronounced effect on mortality and quality of life of stroke patients. Here, we investigate whether this extends to post-stroke fatigue, a major contributor to morbidity after ischemic stroke.

methodsPatients with acute ischemic stroke (recruited consecutively in the STROKE-CARD Registry from 2020 to 2023 at the study center Innsbruck, Austria) were examined for dysphagia via clinical swallowing examination at hospital admission. Post-stroke fatigue was assessed using the Fatigue Severity Scale (FSS) at study specific in person follow-up visits within the first year after ischemic stroke.

resultsAmong 882 ischemic stroke patients (mean age 72.4 ± 13.5 years, 36.8% females), dysphagia was present in 22.0% at hospital admission and persisted in 16.2% until hospital discharge. Post-stroke fatigue affected 52.2% of the total cohort during follow-up and was significantly more prevalent among those with dysphagia (68.4% vs. 49.0%, p < 0.001). The prevalence of fatigue increased with the severity of dysphagia, with the highest proportion (86.7%) in those with severe dysphagia. After multivariable adjustment for other factors associated with post-stroke fatigue, including age, sex, pre-stroke disability, cognitive impairment, stroke severity, inability to walk at discharge, and need for antidepressants at discharge, dysphagia remained independently associated with post-stroke fatigue during the first year after stroke (odds ratio [OR]: 2.03, 95% confidence interval [CI]: 1.22-3.38).

conclusionsDysphagia is common after ischemic stroke and increases the risk of post-stroke fatigue. Patient-tailored measures are warranted to reduce fatigue after stroke and therefore enhance quality of life.

Indexed as

Deglutition DisordersFatigueIschemic StrokeAgedAged, 80 and overAustriaFemaleHumansMaleMiddle AgedRegistriesRisk FactorsSeverity of Illness IndexStrokedysphagiafatigueischemic stroke

Identifiers

PMID39625289
PMCPMC11613211

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.