Evidence map›Paper›PMID 39624951›Full record

ReviewCurrent opinion in infectious diseases2025

Prostate cancer in people with HIV.

Keith Sigel, Ryan Yu, Elizabeth Chiao, Ashish Deshmukh, Michael S Leapman

Abstract readReview
In one paragraph

Review in Current opinion in infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Keith SigelDivision of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
Ryan YuDivision of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
Elizabeth ChiaoDepartment of Epidemiology, University of Texas, MD Anderson Cancer Center, Houston, Texas.
Ashish DeshmukhDepartment of Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina.
Michael S LeapmanDepartment of Urology, Yale School of Medicine, New Haven, Connecticut, USA.

Funding

Optimizing Treatment of Prostate Cancer in Men living with HIVR01CA285342 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Elizabeth Y. Chiao, Ashish A. Deshmukh · 2023 to 2026
$2.7M
TCI Mentored Medical Student Summer Scholars (TCI-MMSSS) ProgramR25CA281789 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI JAMES L. M. FERRARA, JANICE L GABRILOVE · 2023 to 2026
$341k
NCI NIH HHS R01 CA285342NCI NIH HHS R25 CA281789
6 · The paper itself

Abstract

purpose of reviewProstate cancer burden has been rising among people with HIV (PWH), yet it remains understudied in the context of HIV infection. The objective of this review article is to summarize contemporary information on the burden, risk, and outcomes of prostate cancer for people living with HIV. RECENT

findingsDespite a lower apparent incidence of prostate cancer in early studies for PWH compared to uninfected persons, this malignancy is now likely to be the most common tumor for US PWH. Tumor characteristics and stage appear to have limited differences by HIV status. The optimal approach to early detection of prostate cancer remains controversial, and there are little HIV-specific data surrounding screening. Prostate cancer outcomes may have been worse for PWH in the early antiretroviral era but may have improved in more recent years. SUMMARY: Prostate cancer is an increasingly common clinical issue for PWH. Lower than expected incidence rates in the early ART-era may be increasing, and oncologic outcomes may also be improving. Treatment tolerability is still a key question for this patient group. Given the clinical and biological complexity of chronic HIV infection, strategies for both early detection and treatment will need continued evaluation specifically in the setting of HIV.

Indexed as

HIV InfectionsProstatic NeoplasmsEarly Detection of CancerHumansIncidenceMaleRisk Factors

Identifiers

PMID39624951
PMCPMC11695140

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.