Evidence map›Paper›PMID 39624843›Full record

ArticleFrontiers in pharmacology2024

Comparative bactericidal activity of four macrolides alone and combined with rifampicin or doxycycline against

Anne-Sophie Huguet, Ophélie Gourbeyre, Agathe Bernand, Charline Philibert, Alain Bousquet-Melou, Elodie A Lallemand, Aude A Ferran

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Antimicrobial Resistance inAntibiotics (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Review
  4. Integrated molecular and serological survey ofFrontiers in veterinary science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anne-Sophie HuguetINTHERES, INRAE, ENVT, University of Toulouse, Toulouse, France.
Ophélie GourbeyreINTHERES, INRAE, ENVT, University of Toulouse, Toulouse, France.
Agathe BernandINTHERES, INRAE, ENVT, University of Toulouse, Toulouse, France.
Charline PhilibertINTHERES, INRAE, ENVT, University of Toulouse, Toulouse, France.
Alain Bousquet-MelouINTHERES, INRAE, ENVT, University of Toulouse, Toulouse, France.
Elodie A LallemandINTHERES, INRAE, ENVT, University of Toulouse, Toulouse, France.
Aude A FerranINTHERES, INRAE, ENVT, University of Toulouse, Toulouse, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Material and Methods: Therefore, this study was performed to evaluate the Results: Time-kill curves with rifampicin or doxycycline demonstrated a reduction in Conclusion: Our study suggests that clarithromycin can be used either alone or with doxycycline and that its use in combination with rifampicin should be reconsidered. Nevertheless, further studies are required to assess the clinical efficacy and potential side effects of doxycycline in foals.

Indexed as

drug combinationfoallunglung cellsmacrophagesynergy

Identifiers

PMID39624843
PMCPMC11608945

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.