ReviewSkin health and disease2024
Epigenetics and ultraviolet radiation: Implications for skin ageing and carcinogenesis.
Review in Skin health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Palladium-catalysed synthesis of small-molecule epigenetic inhibitors as anticancer therapeutics.Journal of enzyme inhibition and medicinal chemistry · 2026Review
- Dilating the aging clock with light.Innovation (Cambridge (Mass.)) · 2026Review
- Puerarin Reverses UV-Induced Epigenetic Silencing of the Wnt/β-Catenin-KIT Axis to Mitigate Skin Fibroblast Aging.International journal of molecular sciences · 2026Article
- A One Health Perspective on Cancer: A Narrative Review.Medical sciences (Basel, Switzerland) · 2026Review
- [Arnold Rikli and the "atmospheric cure"].Dermatologie (Heidelberg, Germany) · 2026Article
- A New Look at the Role of Radiation-Related Epigenetic Mechanisms in Diagnosis and Anticancer Therapies.Cells · 2025Review
- Persistent Changes in Hormones and Growth Factors Involved in Ageing in Patients That Recovered from Severe COVID-19.Diseases (Basel, Switzerland) · 2025Article
- Dysregulation of autophagy during photoaging reduce oxidative stress and inflammatory damage caused by UV.Frontiers in pharmacology · 2025Review
- Effect of plant-derived exosome-like nanoparticles in ultraviolet-induced skin photoaging.Frontiers in pharmacology · 2025Review
- Epigenetic Clocks in Skin Aging: From Exposome Drivers to Biomarkers and Therapeutic Interventions.Clinical, cosmetic and investigational dermatology · 2025Review
- Epigenetics and ultraviolet radiation: Implications for skin ageing and carcinogenesis.Skin health and disease · 2024Review
- Skin biology and ageing.Skin health and disease · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent published data have highlighted the importance of epigenetics in the response of the skin to recreational and therapeutic ultraviolet radiation (UVR) exposure. 'Epi'-from the Greek επί, meaning over, outside of or around-relates to the chemical modifications that occur on top of the DNA sequence (for example, DNA methylation) and its associated proteins (e.g. histone modifications, including methylation, acetylation and phosphorylation). These epigenetic processes, collectively called the 'epigenome', dictate the three-dimensional conformation of the DNA, thus impacting upon gene expression and genomic stability. Given that epigenetic changes are long-lived and mitotically heritable, an accumulation of epigenetic perturbations likely influence the pathogenesis of the chronic consequences of UVR exposure, including photoageing and skin cancer risk. In this review, we describe the multifarious epigenetic effects elicited by UVR in the skin. We further speculate on the underlying molecular mechanisms that may direct epigenetic changes, such as oxidative stress and changes in metabolism, and their impact on skin health and disease.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.