Evidence map›Paper›PMID 39624737›Full record

ArticleSkin health and disease2024

A cross-sectional study of the vulval dermatology clinic population over a 4-year period and development of a national vulval disease database.

Marianne de Brito, Lisa Kirby, Kate Lomas, Aysha Javed, Caroline Owen, Rosalind Simpson

Abstract read
In one paragraph

Article in Skin health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marianne de BritoDepartment of Dermatology Blackburn Hospital East Lancashire Hospitals NHS Trust Blackburn UK.ORCID https://orcid.org/0000-0002-4156-8634
Lisa KirbyCentre of Evidence Based Dermatology School of Medicine University of Nottingham Nottingham UK.ORCID https://orcid.org/0000-0002-9231-1927
Kate LomasSchool of Medicine University of Nottingham Nottingham UK.
Aysha JavedThe Countess of Chester Hospital NHS Foundation Trust Chester UK.
Caroline OwenDepartment of Dermatology Blackburn Hospital East Lancashire Hospitals NHS Trust Blackburn UK.
Rosalind SimpsonCentre of Evidence Based Dermatology School of Medicine University of Nottingham Nottingham UK.ORCID https://orcid.org/0000-0002-8093-7965

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vulval disease significantly impacts quality of life but is historically under-researched. The epidemiology and aetiology of many vulval conditions is unclear. Data to optimise patient care are lacking. Objectives: To describe the population attending a specialist vulval dermatology clinic and achieve consensus amongst vulval experts on data items to be collected for a future national vulval database. Methods: This descriptive cross-sectional study analysed data that was prospectively collected during clinical contact with consecutive new patients at a vulval dermatology clinic over 4 years.A two-stage electronic-Delphi survey was performed with British vulval experts. Consensus was defined as ≥75% agreement on items for inclusion. Results: The database included 424 (including 29 paediatric) patients. Most patients were White British (71%), with a significant Asian population (13%). Long symptom duration (9.5% > 10 years) and multiple diagnoses, up to 4, were common. Exploratory associations were identified between irritant contact dermatitis and urinary and faecal incontinence, frequent vulval washing and lichen simplex, urinary incontinence and lichen sclerosus and a negative association between candidiasis and age.Following two rounds of the electronic-Delphi survey, consensus was achieved for 18 items that 28 participants agreed were important for a future database. Conclusions: We report disease incidence, patient pathways, outcome measures and potential associations. Though not generalisable, this large UK-based study could inform future projects to improve patient care and support ongoing research, such as a national vulval disease database, for which we also achieve expert consensus on the most valuable items to include.

Identifiers

PMID39624737
PMCPMC11608872

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.