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ArticleRadiology case reports2025

Radiation safety and dialysate analysis in hemodialysis following Lu-177-PSMA-617 therapy: A case report.

Yu-Yi Huang, Ting-Chum Lin, Shih-Han Yang, Lan-Shih Lai, Ling-Man Hung, Ming-Hsin Li, Ching-Yueh Hsia, Kuo-Cheng Huang

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Dosimetry of [EJNMMI research · 2026
    Article
  3. Use ofWiener klinische Wochenschrift · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu-Yi HuangDepartment of Nuclear Medicine, Koo-Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.
Ting-Chum LinDepartment of Nuclear Medicine, Koo-Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.
Shih-Han YangDepartment of Nuclear Medicine, Koo-Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.
Lan-Shih LaiHemodialysis room, Department of Internal Medicine, Koo-Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.
Ling-Man HungDepartment of Nuclear Medicine, Koo-Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.
Ming-Hsin LiDepartment of Nuclear Medicine, Koo-Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.
Ching-Yueh HsiaGlobal Medical Solutions, Taipei, Taiwan.
Kuo-Cheng HuangDepartment of Hematology and Medical Oncology, Koo-Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: We present a patient who is undergoing regular HD and received Lu-177-PSMA-617 treatment, regarding radiation safety issues including environmental radiation, exposure of medical personnel, and the radioactivity in the dialysate. Methods: A 78 years old man with metastatic castration-resistant prostate cancer undergoing HD received 84.4 mCi (3.1 GBq) of Lu-177-PSMA-617. First HD during the 20th-24th hours after injection, and the second HD during 68th-71st hours. The environmental exposure rate and personnel exposure monitoring were measured. The dialysate was collected and sampled, and the activity was measured. Results: During the first HD session, where dialysate was collected in the room, medical personnels received exposure of 3-19µSv. Dialysate was drained out in the second HD, and medical personnels received 2-4 µSv. The radiation exposure rates in the first HD were measured as follows: 3-4 µSv/hr bedside, 1.2-1.5 µSv/hr at 1 meter, and less than 0.3 µSv/hr at 4 meters. In the second HD, the rates were 2-3 µSv/hr bedside, 1.2-1.8 µSv/hr at 1 meter, and less than 0.3 µSv/hr at 4 meters.The dialysate had an activity of 6.88 mCi (0.25 GBq) in 120 liters of the first HD, while in the second HD, it had 2.13 mCi (0.08 GBq) in 90 liters. Conclusion: For the medical personnel involving HD, the accumulative exposure doses were than 2-19 µSv after 20 hour of injection. The environmental exposure rate would drop to background at 4m away from the patient. The dialysate contained minimal amounts of Lu-177 radioactivity.

Indexed as

DialysateHemodialysisLu-177-PSMA-617Radiation safety

Identifiers

PMID39624699
PMCPMC11609536

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