Evidence map›Paper›PMID 39624672›Full record

ArticleFrontiers in neurology2024

Effects of transient, persistent, and resurgent sodium currents on excitability and spike regularity in vestibular ganglion neurons.

Selina Baeza-Loya, Ruth Anne Eatock

Abstract read
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Selina Baeza-LoyaVirginia Merrill Bloedel Hearing Research Center, Department of Otolaryngology-HNS, University of Washington, Seattle, WA, United States.
Ruth Anne EatockDepartment of Neurobiology, University of Chicago, Chicago, IL, United States.

Funding

Auditory Neuroscience Traning ProgramT32DC005361 · NIDCD · UNIVERSITY OF WASHINGTON · PI Adrian KC Lee, DAVID J PERKEL · 2002 to 2026
$8.8M
Synaptic Processing in the Vestibular SystemR01DC012347 · NIDCD · UNIVERSITY OF CHICAGO · PI EATOCK, RUTH ANNE, LYSAKOWSKI, ANNA · 2012 to 2022
$5.2M
NIDCD NIH HHS R01 DC012347NIDCD NIH HHS T32 DC005361
6 · The paper itself

Abstract

Vestibular afferent neurons occur as two populations with differences in spike timing regularity that are independent of rate. The more excitable regular afferents have lower current thresholds and sustained spiking responses to injected currents, while irregular afferent neurons have higher thresholds and transient responses. Differences in expression of low-voltage-activated potassium (K

Indexed as

excitabilityNaV currentspersistent currentregularityresurgent currentspikingvestibular ganglion neurons

Identifiers

PMID39624672
PMCPMC11608953

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.