Evidence map›Paper›PMID 39624556›Full record

ArticleCureus2024

Adherence to Systemic Therapy for Atopic Dermatitis in Adult Patients in Saudi Arabia: A Cross-Sectional Study.

Ali M Aleid, Raghad A Alharbi, Nafisah M Al Radhwan, Nawaf S Alsulamy, Maryam A Alzahrani, Retaj W Calacattawi, Norah H Alsultan, Awatif M Alrasheeday, Faiza Aljarameez, Abbas Al Mutair

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ali M AleidDermatology, Ministry of Health, Riyadh, SAU.
Raghad A AlharbiMedicine, Almaarefa University, Diriyah, SAU.
Nafisah M Al RadhwanInternal Medicine, Medical University of Warsaw, Warsaw, POL.
Nawaf S AlsulamyMedicine, King Abdulaziz University, Jeddah, SAU.
Maryam A AlzahraniMedicine, University of Hail, Hail, SAU.
Retaj W CalacattawiMedicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, SAU.
Norah H AlsultanMedicine, King Faisal University, Hofuf, SAU.
Awatif M AlrasheedayNursing, University of Hail, Hail, SAU.
Faiza AljarameezCritical Care Medicine, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Ministry of the National Guard Health Affairs, Riyadh, SAU.
Abbas Al MutairResearch Center, Almoosa Specialist Hospital, Al Mubarraz, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAtopic dermatitis (AD) is a chronic inflammatory skin disease that significantly impacts both pediatrics and adults. Despite the availability and proven efficacy of systemic medications, there remains a critical issue of non-adherence among patients. This study aimed to assess adherence to systemic therapy among Saudi adult patients with AD.

methodsThe study employed a cross-sectional study with an online questionnaire that was distributed among a convenience sample of 1,154 adult patients with AD in Saudi Arabia. In addition to descriptive statistical analysis, Pearson's correlation and chi-squared tests were used to determine the correlations between adherence to systemic therapy for AD and its predictable factors.

resultsAD was diagnosed over five years in 61.3% of the participants. The vast majority of those diagnosed with AD (73%) were prescribed systemic medications, with a moderate level of adherence to this therapy. While adherence to systemic therapy significantly correlated with improved quality of life, factors including forgetfulness, side effect concerns, patient's belief in medication importance, disease severity, and medication complexity impacted adherence to this mode of therapy. Factors including patient's belief in medication importance, disease severity, and medication complexity impacted adherence.

conclusionThe findings of this study highlight the need for multifaceted interventions to improve adherence to systemic therapy for AD. Addressing patient concerns about the use of systemic therapy for AD and reinforcing the importance of medication use for long-term disease management and quality-of-life improvement is recommended to explore the barriers to adherence and enhance compliance to systemic therapy in this population.

Indexed as

atopic dermatitisdisease severityhealthcare provider monitoringmedication adherencequality of lifesystemic pharmacological interventions

Identifiers

PMID39624556
PMCPMC11610529

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.