Evidence map›Paper›PMID 39624437›Full record

ArticleRSC advances2024

Antimicrobial bianthrones from the crinoid

Vítor F Freire, Lucero Martínez-Fructuoso, Rohitesh Kumar, Rhone K Akee, Christopher C Thornburg, Susan Ensel, Ekene Okoroafor, Jason R Evans, Dongdong Wang, Brian D Peyser and 2 more

Abstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Vítor F FreireNatural Products Branch, Developmental Therapeutic Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute Frederick Maryland 21702-1201 USA.ORCID https://orcid.org/0000-0001-6565-1830
Lucero Martínez-FructuosoNatural Products Branch, Developmental Therapeutic Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute Frederick Maryland 21702-1201 USA.
Rohitesh KumarNatural Products Support Group, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research Frederick Maryland 21702-1201 USA.ORCID https://orcid.org/0000-0002-7187-937X
Rhone K AkeeNatural Products Support Group, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research Frederick Maryland 21702-1201 USA.
Christopher C ThornburgNatural Products Support Group, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research Frederick Maryland 21702-1201 USA.ORCID https://orcid.org/0000-0002-4657-6895
Susan EnselNatural Products Support Group, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research Frederick Maryland 21702-1201 USA.ORCID https://orcid.org/0000-0002-7733-1065
Ekene OkoroaforNatural Products Support Group, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research Frederick Maryland 21702-1201 USA.
Jason R EvansNatural Products Branch, Developmental Therapeutic Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute Frederick Maryland 21702-1201 USA.
Dongdong WangMolecular Targets Program, Center for Cancer Research, National Cancer Institute Frederick Maryland 21702-1201 USA.ORCID https://orcid.org/0000-0002-7824-2507
Brian D PeyserNatural Products Branch, Developmental Therapeutic Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute Frederick Maryland 21702-1201 USA.ORCID https://orcid.org/0000-0002-3455-5181
Tanja GrkovicNatural Products Branch, Developmental Therapeutic Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute Frederick Maryland 21702-1201 USA.ORCID https://orcid.org/0000-0002-6537-3997
Barry R O'KeefeNatural Products Branch, Developmental Therapeutic Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute Frederick Maryland 21702-1201 USA.ORCID https://orcid.org/0000-0003-0772-4856

Funding

NCI Program for Natural Products Discovery - CuresZIABC011854 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI OKEEFE, BARRY · 2020 to 2025
$5.2M
CCR NIH HHS HHSN261200800001CIntramural NIH HHS ZIA BC011854NCI NIH HHS HHSN261200800001E
6 · The paper itself

Abstract

Antimicrobial resistance is a global public health problem and identification of new chemical scaffolds is important to overcoming this threat. In a recent high-throughput discovery campaign, fractions derived from the organic extract of crinoid,

Identifiers

PMID39624437
PMCPMC11610039

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.