Evidence map›Paper›PMID 39624389›Full record

ArticleERJ open research2024

Vasoreactivity and inhaled treprostinil response in interstitial lung disease pulmonary hypertension.

Eileen M Harder, Farbod N Rahaghi, Jane A Leopold, David M Systrom, George R Washko, Aaron B Waxman

Abstract read
In one paragraph

Article in ERJ open research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eileen M HarderBrigham and Women's Hospital, Division of Pulmonary and Critical Care Medicine, Boston, MA, USA.
Farbod N RahaghiBrigham and Women's Hospital, Division of Pulmonary and Critical Care Medicine, Boston, MA, USA.
Jane A LeopoldBrigham and Women's Hospital, Division of Cardiovascular Medicine, Boston, MA, USA.
David M SystromBrigham and Women's Hospital, Division of Pulmonary and Critical Care Medicine, Boston, MA, USA.
George R WashkoBrigham and Women's Hospital, Division of Pulmonary and Critical Care Medicine, Boston, MA, USA.
Aaron B WaxmanBrigham and Women's Hospital, Division of Pulmonary and Critical Care Medicine, Boston, MA, USA.ORCID https://orcid.org/0000-0001-7797-0361

Funding

RESPIRATORY RESEARCHT32HL007633 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI George R Washko · 1985 to 2026
$14.9M
NHLBI NIH HHS T32 HL007633
6 · The paper itself

Abstract

Introduction: Despite shared features with pulmonary arterial hypertension, acute vasoreactivity in pulmonary hypertension with interstitial lung disease (PH-ILD) is not well characterised, including its potential ability to predict therapeutic outcomes. We sought to determine whether acute vasoreactivity in PH-ILD to oxygen (O Materials and methods: In this retrospective cohort analysis, we identified treatment-naive PH-ILD patients with vasoreactivity testing using O Results: Among 75 PH-ILD patients, mean pulmonary arterial pressure (mPAP) decreased by -3 mmHg (-12.6%) and pulmonary vascular resistance (PVR) by -1.3 WU (-23.7%) with O Conclusions: In PH-ILD, the microvascular response to O

Identifiers

PMID39624389
PMCPMC11609945

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.