Assessment of clinical efficacy and safety of ICL implantation in patients with relatively shallow anterior chamber depth in early and midterm postoperative time.

Objective: To investigate the clinical effect and safety of Implantable Collamer Lens (ICL) implantation in myopic patients with relatively shallow anterior chamber depth (ACD). Methods: Retrospective analysis, comparative, non-interventional case series. Patients with myopia who underwent ICL implantation were included in the study and were categorized into two groups: one with a relatively shallow ACD (2.60 mm ≤ ACD ＜ 2.80 mm) and the other with a normal ACD (ACD ≥2.80 mm). Each group comprised 51 eyes and were reviewed for at least 6 months. To evaluate preoperative and postoperative visual acuity, intraocular pressure (IOP), central vault, ACD, endothelial cell density (ECD) and anterior chamber angle parameters [ trabecular iris angle (TIA), angle opening distance at 500 μm and 750 μm (AOD500, AOD750), trabecular iris space area at 500 μm and 750 μm (TISA500, TISA750) ]. Analyze the trend of postoperative data changes of 1 week, 1 month, 3 months, and at least 6 months. Patients in relatively shallow ACD with vault <100 μm or >1000 μm were performed detailed follow-up. Results: The postoperative uncorrected distance visual acuity (UDVA) and best corrected visual acuity (BCVA) surpassed the preoperative BCVA in two groups. The group differences of effectiveness index (EI) was Conclusion: Patients with relatively shallow ACD who underwent ICL implantation had fine postoperative clinical efficacy and safety.