ArticleDEN open2025
A rectal ulcer caused by hydrogel spacer insertion: A case report and review of the literature.
Article in DEN open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Fournier's Gangrene Following Hydrogel Spacer-related Rectal Ulcer and Fistula in a Patient Undergoing Radiation Therapy for Prostate Cancer.Internal medicine (Tokyo, Japan) · 2026Article
- Robot-Assisted Radical Prostatectomy in a Patient With a Rectal Fistula Following Hydrogel Spacer Placement.IJU case reports · 2026Article
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 75-year-old man presented with hematochezia. He had been diagnosed with prostate cancer (stage 1) 1 month previously and had undergone gold marker injection and hydrogel spacer insertion 3 weeks previously to prepare for radiotherapy. Hydrogel spacer insertion is a safe procedure that can prevent the side effects of radiotherapy for prostate cancer. A computed tomography evaluation identified a low-density area that extended from the prostate to the rectal wall. Magnetic resonance imaging of the abdomen revealed the hydrogel spacer between the anterior rectal wall and prostate. A colonoscopy revealed an approximately 2 cm ulcer in the rectum. The patient was diagnosed with a rectal ulcer with bleeding caused by hydrogel spacer insertion. Conservative follow-up was performed, and his condition improved over time. Radiotherapy for prostate cancer was initiated 4 months after hydrogel spacer insertion. The patient has not experienced any abdominal symptoms such as bloody stools since that time. Because the incidence of prostate cancer is increasing, the number of such cases is likely to increase in the future.
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Registered trials
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