Evidence map›Paper›PMID 39624104›Full record

ArticleFrontiers in pediatrics2024

Causal relationship between the composition of the Gut Microbiota and central precocious puberty: a two-sample Mendelian randomization study.

Minhong Chen, Xueqin Huang, Wanhong Huang, Chuangang Ding

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Minhong ChenSchool of Clinical Medicine, Dali University, Dali, China.
Xueqin HuangDepartment of Pediatrics, Jingzhou Maternity and Child Health Hospital, Jingzhou, China.
Wanhong HuangGuangzhou Medical University, Guangzhou, China.
Chuangang DingDepartment of Pediatrics, The First Affiliated Hospital of Dali University, Dali, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Previous observational research has demonstrated a possible association between the gut microbiota (GM) and central precocious puberty (CPP). Nevertheless, whether there is a causal relationship between the GM and CPP is uncertain due to the possibility of confounding factors influencing the result. Methods: We collected summary data from genome-wide association studies of the GM (MiBioGen, Results: According to the inverse-variance weighted average technique, there was a substantial correlation between CPP and the composition of the GM. Specifically, the relative abundance of the genus Conclusions: The composition of the GM may have a causal effect on CPP. The present finding that

Indexed as

causal relationshipcentral precocious pubertygeneticsgut microbiotaMendelian randomization

Identifiers

PMID39624104
PMCPMC11609932

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.