Evidence map›Paper›PMID 39624090›Full record

ArticleFrontiers in immunology2024

Estimation of PfRh5-based vaccine efficacy in asymptomatic

Hojong Jun, Ernest Mazigo, Wang-Jong Lee, Johnsy Mary Louis, Jadidan Hada Syahada, Fadhila Fitriana, Jin Heo, Yeonkyung Kim, Boeun Kwon, Fauzi Muh and 15 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Serological evidence of continued exposure toFrontiers in microbiology · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Hojong JunDepartment of Medical Environmental Biology and Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Ernest MazigoDepartment of Medical Environmental Biology and Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Wang-Jong LeeDepartment of Medical Environmental Biology and Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Johnsy Mary LouisDepartment of Medical Environmental Biology and Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Jadidan Hada SyahadaDepartment of Medical Environmental Biology and Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Fadhila FitrianaDepartment of Medical Environmental Biology and Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Jin HeoDepartment of Medical Environmental Biology and Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Yeonkyung KimDepartment of Medical Environmental Biology and Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Boeun KwonDepartment of Medical Environmental Biology and Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Fauzi MuhFaculty of Public Health, Department of Epidemiology and Tropical Diseases, Universitas Diponegoro, Semarang, Indonesia.
Feng LuDepartment of Pathogen Biology and Immunology, School of Medicine, Yangzhou University, Yangzhou, China.
Md Atique AhmedMalaria Division, Indian Council of Medical Research (ICMR)-Regional Medical Research Centre, Dibrugarh, Assam, India.
Se Jin LeeDepartment of Obstetrics and Gynecology, Kangwon National University Hospital, Chuncheon, Republic of Korea.
Sunghun NaDepartment of Obstetrics and Gynecology, Kangwon National University Hospital, Chuncheon, Republic of Korea.
Wanjoo ChunDepartment of Pharmacology, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Won Sun ParkDepartment of Physiology, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Min HongInstitute of Biological Resources, Chuncheon Bioindustry Foundation, Chuncheon, Republic of Korea.
Joon-Hee HanInstitute of Biological Resources, Chuncheon Bioindustry Foundation, Chuncheon, Republic of Korea.
Tae-Hyung KwonInstitute of Biological Resources, Chuncheon Bioindustry Foundation, Chuncheon, Republic of Korea.
Soo-Ung LeeInstitute of Biological Resources, Chuncheon Bioindustry Foundation, Chuncheon, Republic of Korea.
Eun-Teak HanDepartment of Medical Environmental Biology and Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Jim ToddDepartment of Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Alphaxard ManjuranoDepartment of Parasitic Diseases, National Institute for Medical Research, Dar es Salaam, Tanzania.
Winifrida KidimaDepartment of Zoology, College of Natural and Applied Sciences, University of Dar es Salaam, Dar es Salaam, Tanzania.
Jin-Hee HanDepartment of Medical Environmental Biology and Tropical Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: Samples for this study were collected from four villages in each of the Kigoma and Geita regions, known malaria transmission hotspots in Tanzania. This community-based cross-sectional study was conducted from December 2022 to July 2023. Genetic variation and natural selection pressure on Results: The results revealed that Conclusions: These findings underscore the need for future PfRh5-based vaccines to consider for increasing genetic variation and geographical differences in humoral immune responses.

Indexed as

Antigenic VariationAntigens, ProtozoanMalaria, FalciparumMalaria VaccinesPlasmodium falciparumAdolescentAdultAntibodies, ProtozoanCarrier ProteinsChildChild, PreschoolCross-Sectional StudiesEndemic DiseasesFemaleGenetic VariationHumansAntibodies, ProtozoanAntigens, ProtozoanCarrier ProteinsMalaria VaccinesProtozoan ProteinsRH5 protein, Plasmodium falciparumantigenicity variationasymptomaticgenetic variationmalariaPfRh5Plasmodium falciparumTanzaniavaccine

Identifiers

PMID39624090
PMCPMC11609159

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.